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Comparison of Intraoperative Pain Perception During Caries Excavation Using Smart Burs and Carisolv to Conventional Diamond Burs

Sponsor: Rehman Medical Institute - RMI • ClinicalTrials.gov ID: NCT07869407

Registry updated: 2026-10-09

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Description

The goal of this randomized controlled trial is to compare the amount of pain experienced during removal of dental caries using Smart burs, Carisolv, and conventional diamond burs in adults aged 18-45 years with active caries in asymptomatic mandibular molars. The main questions it aims to answer are: Does the method used for caries removal affect the amount of pain experienced? Is there a difference in pain perception between Smart burs, Carisolv, and conventional diamond burs? Researchers will compare the three treatment groups to see whether pain perception during caries excavation differs between the methods. Participants will: Be randomly assigned to one of three groups: Smart burs, Carisolv, or conventional diamond burs. Undergo caries removal using the assigned method. Rate their pain during the procedure using a 0-10 Visual Analogue Scale (VAS).

Interventions

polymer burs (Device)
Carious dentin will be selectively excavated using Smart polymer burs operated at low speed (500-800 rpm), aiming to preserve sound dentin.
Carisolv (Device)
Carious dentin will be chemically softened using Carisolv gel and subsequently removed with hand instruments.
Conventional Diamond Burs (Device)
Carious dentin will be removed using conventional rotary diamond burs under standard clinical operative dentistry procedures.

Eligibility criteria

Inclusion Criteria: * Be male or female. * Be 18-45 years of age. * Have at least one active carious lesion with exposed dentin in an asymptomatic mandibular molar. * Have an ICDAS II Code 5 lesion: a dentinal cavity clearly visible clinically, with the cavity surface feeling soft or leathery on gentle probing. * Have a radiograph showing a clear band of dentin between the carious lesion and the pulp. * Provide written informed consent to participate. Exclusion Criteria: * Symptoms/signs of pulpitis. * Pulp exposure. * Abscess formation, including swelling, redness, or a fistula adjacent to the affected tooth. * Necrotic pulp, indicated by lack of response to cold testing. * Cardiovascular disease. * Diabetes mellitus. * Hypertension. * Severe periodontal disease. * Pregnancy. * Unwillingness or inability to provide informed consent/participate.

Conditions

Pain During Caries Excavation

Locations

Rehman College of Dentistry — Peshawar, Khyber Pakhtunkhwa, Pakistan

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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