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Active Release and Myofascial Release Technique in Patients With Patellofemoral Pain Syndrome

Sponsor: Riphah International University • ClinicalTrials.gov ID: NCT07854041

Registry updated: 2026-10-02

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Description

Patellofemoral pain syndrome (PFPS) is often associated with imbalance and weakness in several key muscle group. These include the quadriceps (especially the vastus medialis oblique), hip abductors and external rotators and hamstrings as well as tightness in iliotibial band and gastrocnemius. Exercises involving isometrics, stretching, strengthening of knee along with core muscles has improved range, strength, coordination and motor control. This study aim to determine the effects of active release along with myofascial release technique on pain, range of motion and function in patients with patellofemoral pain syndrome. This study will be a randomized controlled trial and will be conducted in Riphah Rehabilitation Clinic Lahore (Physiotherapy Department) and Ghurki Trust Hospital Lahore. Non-probability consecutive sampling will be used to collect the data. Sample size of 30 subjects with age group between 15-40 years will be taken. Data will be collected from the patients having present complaint of anterior knee pain. Outcome measures will be taken by using Numeric pain rating scale (NPRS), Anterior knee pain scale (AKPS)for pain, Universal Goniometer (GU) for Range of motion and KOOS PS scale to assess physical function in patient with knee pain. An informed consent will be taken. Subjects will be selected on the basis of inclusion and exclusion criteria and will be equally divided into two groups by random number generator table. Both the Groups will receive RICE protocol, ice, stretching, strengthening and knee isometrics exercises, while Group A will receive active release and Group B will receive myofascial release technique. Outcome measures will be measured at baseline and after 6 weeks. Data analysis will be done by SPSS version 25.

Interventions

Group A (Other)
Before applying active release technique, assess the knee joint, by palpating the area of tightness, tenderness and restricted movement .Then apply specific pressure to affected tissues, such as the quadriceps, hamstrings, iliotibial band (IT band) or patellar tendon, depending on the findings of the evaluation. The patient will then actively move the knee joint through prescribed range of motions, while the therapist maintain contact and provides appropriate pressure. This process is repeated several times, with the therapist adjusting pressure and movements as needed to improve tissue mobility and reduce pain.
Group B (Other)
For Myofascial release technique therapist will use their hands to apply sustained pressure to restricted areas fascia, gradually lengthening and releasing the tissue. Gentle stretching techniques can also be used to lengthen the tissue and muscles, improving flexibility and range of motion.

Eligibility criteria

Inclusion Criteria: * Experience retro patellar pain for at least three months, including pain at rest or during activities such as ascending or descending stairs, jumping, running, squatting, kneeling, or prolonged sitting (12). * Patients with + ive Squat test in the absence of any pathology * Patients also must have presented with an insidious onset of symptoms unrelated to trauma and a positive Clark test (19). * Reduced knee range of motion, especially extension Exclusion Criteria: * A history of significant lower extremity, pelvic, or spinal surgery/fracture, or traumatic lesions of ligaments or meniscus within the past six months. * Presence of other orthopedic conditions (e.g., ACL rupture, meniscal tears), neurological disorders (e.g., multiple sclerosis, paralysis), rheumatological diseases (e.g., rheumatoid arthritis, ankylosing spondylitis), or congenital conditions leading to osteoarthrosis. * Current pregnancy * A history of connective tissue disease, patellofemoral dislocation or subluxation, osteoarthrosis of the knees. Other forms of anterior knee pain (e.g., Osgood-Schlatter disease, tendon pain, bursitis). A history of referred pain from the lumbar spine (12). or

Conditions

Patello Femoral Pain Syndrome

Locations

Riphah Rehabilitation Clinic — Lahore, Punjab Province, Pakistan

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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