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Virtual Reality Aniseikonia and Metamorphopsia Testing

Sponsor: NYU Langone Health • ClinicalTrials.gov ID: NCT07838181

Registry updated: 2026-09-24

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Description

The purpose of this study is to assess whether the use of small, lightweight, portable virtual reality headset devices can provide a more accessible, reliable, contained, and convenient testing environment compared to previous platforms. Many tests only assess distortions in one plane or meridian and may have confounding effects from factors such as external stimuli or the use of colored filters to selectively display images to each eye. The investigators hypothesize that this device will help minimize, if not get rid of, a lot of these confounding factors that exist currently.

Interventions

Aegenta VR (Device)
The Aegenta VR system is a custom software application designed to operate with a virtual reality (VR) headset platform, such as a smartphone paired with a Google Cardboard V2 viewer. The application presents visual stimuli to each eye and allows users to identify perceived distortions and magnification changes. These responses are used to generate quantitative measures of metamorphopsia and aniseikonia.

Eligibility criteria

Inclusion Criteria: * Over 18 years of age * Have no reported visual distortions with a negative Amsler test; or * Have visual distortions with a positive Amsler grid test and an ocular history of one of the following: epiretinal membrane (ERM), age-related Macular degeneration (AMD), central serous retinopathy (CSR), diabetic macular edema (DME), cystoid macular edema (CME) * Ophthalmology residents, staff, and physicians Exclusion Criteria: * Eye pathology limiting view to the posterior pole to obtain adequate quality fundus photograph or OCT imaging in either eye * Impaired visual acuity with best-corrected visual acuity equal to or worse than 20/70 * Motor deficits of the upper extremities

Conditions

Metamorphopsia Aniseikonia

Locations

NYU Langone Health — New York, New York, United States

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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