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Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic Surgery

Sponsor: Fan Zhang • ClinicalTrials.gov ID: NCT07837427

Registry updated: 2026-09-23

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Description

This study is being done to find out if the height of the fluid bag and the direction of the surgical cut affect the pressure of the fluid used during unilateral biportal endoscopic (UBE) spine surgery. UBE is a minimally invasive surgery for the spine. During this surgery, fluid is used to keep the surgical area clear and to control bleeding. The pressure of this fluid may affect how clear the surgical view is, how much bleeding occurs, and how well patients recover after surgery. We will also collect disc tissue removed during surgery to study how disc degeneration is related to factors such as sex, age, mechanical stress, and injury. About 80 patients aged 18 to 75 who are scheduled for UBE surgery at our hospital will take part. Patients will be randomly assigned to one of four groups based on two things: the height of the fluid bag (0.9 meters or 1.0 meters) and the direction of the surgical cut (horizontal or vertical). We will measure the fluid pressure around the spinal covering during surgery and record how clear the surgical view is. After surgery, we will track patients' pain and recovery for at least 6 months. This study has been approved by the hospital ethics committee.

Interventions

Unilateral Biportal Endoscopic Surgery (Procedure)
UBE surgery performed with specified fluid bag height (0.9 m or 1.0 m) and incision direction (transverse or longitudinal).

Eligibility criteria

Inclusion Criteria: * Age \>= 18 years and \< 75 years. * Patients scheduled for unilateral biportal endoscopic (UBE) surgery for lumbar degenerative disease at the First Affiliated Hospital of Kunming Medical University between February 2026 and December 2027. * Follow-up duration \> 6 months. * Complete clinical and follow-up data available. * Voluntary participation and signed informed consent. Exclusion Criteria: * History of tuberculosis, infection, tumor, or trauma. * Severe cardiac, hepatic, or renal insufficiency. * History of chronic lung disease, liver disease, HIV infection, diabetes, or renal insufficiency. * Psychiatric disorders or inability to comply with follow-up. * Severe osteoporosis. * Pregnant or lactating women.

Conditions

Lumbar Disc Herniation Lumbar Spinal Stenosis Lumbar Degenerative Disease

Locations

The First Affiliated Hospital of Kunming Medical University — Kunming, Yunnan, China

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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