RECRUITING Not applicable ClinicalTrials.gov

Impact of Concomitant TURP on Bladder Stone Surgery Outcomes

Sponsor: Beni-Suef University • ClinicalTrials.gov ID: NCT07831486

Registry updated: 2026-09-21

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Description

The management of bladder stones secondary to benign prostatic hyperplasia (BPH) remains controversial regarding whether transurethral resection of the prostate (TURP) should be performed concomitantly or selectively. The primary objective of this prospective randomized comparative study is to compare the postoperative outcomes of cystolitholapaxy alone versus cystolitholapaxy with concomitant TURP in adult male patients presenting with bladder calculi secondary to BPH. Additionally, the study aims to identify clinical and urodynamic predictors for requiring subsequent (delayed) TURP among patients initially treated with stone surgery alone.

Interventions

Transurethral Cystolitholapaxy Alone (Procedure)
Transurethral fragmentation and evacuation of bladder calculi using standard endourological equipment without surgical intervention for the prostate at the time of stone surgery.
Transurethral Resection of the Prostate (TURP) (Procedure)
Transurethral resection of the prostate to relieve bladder outlet obstruction, performed in the same operative session as cystolitholapaxy.

Eligibility criteria

Inclusion Criteria: * Adult men aged 40 years or older. * Lower urinary tract symptoms (LUTS) attributed to benign prostatic hyperplasia (BPH). * International Prostate Symptom Score (IPSS) \>= 8. * Prostate size \>= 30 grams (measured by ultrasonography). * Maximum urinary flow rate (Qmax) \<= 15 mL/s. * Presence of urinary bladder calculus/calculi confirmed by diagnostic imaging. * Written informed consent provided prior to study enrollment. Exclusion Criteria: * Evidence or history of urethral stricture. * Known or suspected prostate cancer. * Known or suspected bladder cancer / urothelial malignancy. * Neurogenic bladder dysfunction. * Chronic urinary retention with overflow incontinence. * Previous prostate or bladder neck surgery (e.g., prior TURP, TUIP, open prostatectomy). * Active urinary tract infection (UTI) at the time of surgery (patients treated for infection preoperatively may be reassessed for eligibility).

Conditions

Bladder Stone

Locations

Faculty of Medicine, Beni-Suef University — Banī Suwayf, Beni Suweif Governorate, Egypt

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record

Accelerate Your Clinical Trial Recruitment