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AI-Assisted Personalized Heat-Risk Alerts

Sponsor: National University of Medical Sciences, Pakistan • ClinicalTrials.gov ID: NCT07825831

Registry updated: 2026-09-23

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Description

This two-arm randomized controlled trial will evaluate whether an artificial intelligence-assisted personalized heat-risk alert system reduces heat-related illness symptom burden among adults with chronic conditions. The intervention will integrate prespecified clinical characteristics with the Pakistan Meteorological Department's same-day forecast maximum temperature to classify individual heat-related acute clinical-event risk and deliver personalized alerts through a mobile application. The control group will receive a generic PMD heat-health advisory through the same application.

Interventions

AI-Assisted Personalized Heat-Risk Alert System (Behavioral)
A mobile application-based heat-health alert system that uses a locked AI prediction engine to integrate prespecified individual clinical characteristics with the Pakistan Meteorological Department's same-day forecast maximum temperature (≥36°C) and classify participants into low, moderate, or high heat-related acute clinical-event risk categories. The application delivers corresponding personalized heat-health messages.
Generic PMD Heat-Health Advisory (Behavioral)
Generic Pakistan Meteorological Department heat-health advisory delivered through the same patient-facing mobile application when the same-day forecast maximum temperature is ≥36°C, without AI-based risk stratification or individualized clinical personalization.

Eligibility criteria

Inclusion Criteria: * Adults aged 18 years or older attending the outpatient department of the selected tertiary-care hospital during the recruitment period. * Have a documented diagnosis of at least one chronic non-communicable disease associated with increased susceptibility to heat-related illness, including hypertension, type 2 diabetes mellitus, chronic kidney disease, cardiovascular disease, or obesity (BMI ≥30 kg/m²). * Have access to a personal smartphone capable of receiving study heat-risk alert notifications. * Be able to read Urdu or English, or have a household member/caregiver available to read and explain study alerts when required. * Be willing and able to provide written informed consent. * Intend to remain within the study catchment area for the duration of the six-week study period to facilitate follow-up. Exclusion Criteria: * Patients requiring immediate emergency treatment or hospital admission at the time of recruitment. * Individuals with severe cognitive impairment, dementia, psychotic illness, or another medical condition that limits their ability to understand study procedures or provide informed consent. * Patients with terminal illness or those receiving palliative care. * Individuals with severe visual, hearing, or communication impairments that prevent effective receipt of the study alert intervention and outcome assessment without a reliable caregiver. * Pregnant women, because pregnancy has distinct physiological responses to heat exposure and would require separate clinical risk stratification beyond the scope of this study. * Participants currently enrolled in another clinical trial or structured behavioral intervention related to heat-health, climate adaptation, or chronic disease self-management. * Participants who are unable or unwilling to comply with study procedures or complete the required follow-up assessment.

Conditions

Heat-related Illness Chronic Disease

Locations

DHQ Teaching Hospital Gujranwala — Gujranwala, Punjab Province, Pakistan

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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