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RECRUITING Not applicable ClinicalTrials.gov

Peroxide Versus Non-Peroxide In-Office Tooth Bleaching

Sponsor: Minia University • ClinicalTrials.gov ID: NCT07818031

Registry updated: 2026-10-15
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Description

This randomized clinical trial aims to compare the effectiveness of peroxide and non-peroxide in-office tooth bleaching systems. The study will evaluate tooth whitening efficacy, color durability over time, and tooth sensitivity after treatment. Participants will receive one of the two bleaching treatments and will be followed for six months to assess the clinical outcomes and compare the performance of both systems.

Interventions

  • peroxide -based in office tooth bleaching (Procedure)
    Participants will receive an in-office peroxide-based tooth bleaching treatment using the bleaching system according to the manufacturer's instructions.
  • non-peroxide -based in office tooth bleaching (Procedure)
    Participants will receive an in-office non- peroxide-based tooth bleaching treatment using the bleaching system according to the manufacturer's instructions.

Eligibility criteria

Inclusion Criteria: * Adults aged 18-45 years. * Good general health. * Presence of all maxillary anterior teeth free from restorations, caries, or structural defects. * Baseline tooth shade suitable for bleaching assessment. * Good oral hygiene and periodontal health. * Willingness to comply with the study protocol and attend all follow-up visits. * Signed informed consent. Exclusion Criteria: * Pregnancy or lactation. * History of tooth hypersensitivity. * Active caries or defective restorations in the anterior teeth. * Intrinsic tooth discoloration (e.g., fluorosis, tetracycline staining). * Ongoing orthodontic treatment. * Smoking. * Use of tooth-whitening products within the previous 6 months. * Allergy to any component of the bleaching materials.

Conditions

Tooth Discoloration Tooth Staining

Locations

  • Minia University Hospital — Minya, Minya Governorate, Egypt
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record