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Randomized Assessor-Masked Trial of Moderate Graduated Compression Stockings for Popliteal Vein Dilation During Long-Haul Economy-Class Air Travel After Aesthetic Surgery

Sponsor: Research Inc • ClinicalTrials.gov ID: NCT07810192

Registry updated: 2026-09-09

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Description

This randomized assessor-masked trial will evaluate whether knee-high moderate graduated compression stockings reduce popliteal vein dilation during long-haul economy-class air travel to Bogota. Participants will be assigned to stockings or no stockings and will undergo bilateral ultrasound before flight, within 2 hours after arrival, and at 24 and 48 hours. The primary outcome is the between-group difference in change in mean bilateral popliteal vein diameter from preflight baseline to arrival.

Interventions

Enoxaparine (Drug)
All patients got enoxaparin to prevent blood clots
Knee-High Graduated Compression Stockings (Device)
PROPOSED pressure class: 20-30 mmHg at the ankle, appropriately sized according to calf and ankle circumference, worn from approximately 1 hour before boarding until completion of the arrival ultrasound. The final product, pressure class, fitting method, and wear instructions must be confirmed. Linked arm/group(s): Moderate Compression Stockings.
Standardized Bilateral Popliteal Vein Ultrasound (Diagnostic test)
Triplicate bilateral diameter and cross-sectional-area measurements after a standardized rest period, with compressibility and flow assessment by an assessor masked to allocation. Linked arm/group(s): Moderate Compression Stockings, No Compression Stockings.

Eligibility criteria

Inclusion Criteria: * Age 18 to 65 years. * Economy-class commercial itinerary to Bogota with at least 4 hours of total airborne time. * No clinical indication that mandates or prohibits compression stockings. * Ability to obtain the assigned stocking before boarding and wear it as instructed. * Standardized preflight and postarrival ultrasounds completed before surgery. * Written informed consent. Exclusion Criteria: * Current deep venous thrombosis, therapeutic anticoagulation, or severe peripheral arterial disease. * Significant lower-limb skin disease, ulceration, neuropathy, or deformity preventing safe stocking use. * Pregnancy. * Planned use of another compression device during the flight. * Surgery or major intravenous fluid therapy before completion of the 48-hour examination. * Inability to complete preflight ultrasound or follow assigned treatment.

Conditions

Physiologic Venous Dilation Air Travel

Locations

Clinica INO — Bogotá, Colombia

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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