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RECRUITING Not applicable ClinicalTrials.gov

To Evaluate If Preoperative 7 Days Low Calorie Diet Reduces Postoperative Morbidity in Liver Surgery

Sponsor: Region Skane • ClinicalTrials.gov ID: NCT07801716

Registry updated: 2026-09-03
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Description

The rationale for this study is to evaluate whether a standardized, preoperative, short-term Low Calorie Diet (LCD) reduces intraoperative bleeding and postoperative morbidity in liver surgery. Participants with a BMI of 30 or higher, scheduled for liver surgery, if accepting participation, will be randomized to a 7 day LCD or no intervention. A previous small single center RCT have shown significantly reduced intraoperative blood loss and a tendency towards less postoperative complications. This multi-centre study aims to include enough patients with power to analyze also postoperative complications.

Interventions

  • Low calorie meal replacement plan (Dietary supplement)
    Short-term LCD one week prio to liver surgery for patients with a BMI 30 or higher

Eligibility criteria

Inclusion Criteria: * Scheduled for open or minimally invasive liver resection * BMI ≥30 Exclusion Criteria: * Diagnosed liver cirrhosis * Perihilar tumours * Inability to understand written information in Swedish, Norwegian, Danish, or English

Conditions

Surgical Complications

Locations

  • Department och Surgery, Skane University Hospital — Lund, Sweden
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record