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Influence of Irrigant Delivery Systems on the Incidence of Postoperative Discomfort in Oval Canals

Sponsor: Minia University • ClinicalTrials.gov ID: NCT07788027

Registry updated: 2026-08-26

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Description

The main aim of endodontic therapy is to disinfect the entire root canal system (RCS), which requires the elimination of microorganisms and microbial components. This goal is pursued by chemo-mechanical debridement of the RCS. Attaining this goal remains challenging due to the complex and variable anatomy of the root canal system, which includes intricate structures such as fins, isthmuses, lateral canals, and apical deltas that are often inaccessible to mechanical instrumentation. To overcome these anatomical limitations, various irrigation protocols have been developed to enhance the penetration and effectiveness of irrigating solutions.The use of different activation techniques-such as manual dynamic agitation, irrigation needle, sonic and ultrasonic activation, and negative pressure irrigation systems-aims to improve the distribution, exchange, and cleaning ability of irrigants within hard-to-reach areas of the canal system.These approaches are designed to maximize microbial reduction and promote more effective removal of debris and smear layer remnants.

Interventions

Sodium hypochlorite 5.25% (Drug)
to compare the effect of all different irrigation and activation protocols manual agitation, conventional needle irrigation, sonic activation, and negative pressure systems (such as Safe Clean) on the incidence and intensity of postoperative pain following endodontic treatment of canines and premolars

Eligibility criteria

Inclusion Criteria: * Inclusion Criteria Patients aged between 18 and 45 years. * Patients requiring primary root canal treatment. * Patients in good general health.. * Subjects classified as ASA-1 following the classification proposed by the American Society of Anesthesiologists. Exclusion Criteria: * Patients with systemic diseases affecting pain perception or healing. * Patients who had taken analgesics or antibiotics within 12-24 hours prior to treatment. * Pregnant or lactating women. * Previously treated teeth or teeth with root resorption, fractures, or severe periodontal disease. .

Conditions

Post Operative Pain

Locations

Endodontics Department Faculty of Dentistry — Minya, Egypt

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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