Real-World Effectiveness and Safety of Pegcetacoplan in Patients With C3G or IC-MPG: A Multi-Country Study

Description

The purpose of this study is to evaluate the effectiveness and safety of Pegcetacoplan in patients with C3G and primary IC-MPGN in the real-world setting. This study will also assess biomarkers not routinely measured in clinical practice. Results will support the long-term evaluation of the benefit-risk profile of pegcetacoplan in a broad patient population, informing clinical decision-making.

Interventions

• Pegcetacoplan (Drug)
  Solution for infusion for subcutaneous use according to drug use in the real world.

Eligibility criteria

Conditions

Locations

• Nepean Hospital — Kingswood, Australia
• Princess Alexandra Hospital — Woolloongabba, Australia
• Medizinische Universität Graz — Graz, Austria
• Uniklinik Innsbruck — Innsbruck, Austria
• Allgemeines Krankenhaus Wien Universitätsklinik — Vienna, Austria
• Klinik Ottakring — Vienna, Austria
• Cliniques Universitaires Saint-Luc — Brussels, Belgium
• University hosptial of Antwerpen — Edegem, Belgium
• Grand Hôpital de Charleroi — Gilly, Belgium
• UZ Leuven — Leuven, Belgium
• Centre Hospitalier Universitaire de Liege — Liège, Belgium
• CHU UCL Namur — Namur, Belgium
• University of Calgary - Alberta Children's Hospital — Calgary, Alberta, Canada
• British Columbia Childrens' & Women's Hospital Center — Vancouver, British Columbia, Canada
• Kingston General Hospital — Kingston, Ontario, Canada
• London Health Sciences Centre (LHSC) - Victoria Hospital — London, Ontario, Canada
• The Hospital for Sick Children — Toronto, Ontario, Canada
• University Health Network — Toronto, Ontario, Canada
• McGill University — Montreal, Quebec, Canada
• CHU Sainte-Justine — Montreal, Quebec, Canada
• Institut klinicke a experimentalni mediciny — Prague, Czechia
• Fakultni nemocnice v Motole — Prague, Czechia
• CHU Bordeaux — Bordeaux, France
• CHU Lyon - Hôpital Femme-Mère-Enfant — Bron, France
• Hopital Henri Mondor — Créteil, France
• Hopital Claude Huriez - CHU Lille — Lille, France
• Hopital de la Conception - APHM — Marseille, France
• Hopital Lapeyronie pt — Montpellier, France
• CHU Nantes - Hôtel Dieu — Nantes, France
• Hôpital Saint-Louis — Paris, France
• AP-HP Georges-Pompidou European Hospital (Paris) — Paris, France
• Hôpital Necker - Enfants Malades — Paris, France
• Hôpital Robert Debré - Paris — Paris, France
• Tenon CHU Paris Est — Paris, France
• CHU Reims - Hôpital Maison Blanche — Reims, France
• CHU Strasbourg - Nouvel Hôpital Civil — Strasbourg, France
• Hôpital Foch — Suresnes, France
• Universitaetsklinikum Aachen AOeR — Aachen, Germany
• Charité - Campus Virchow-Klinikum — Berlin, Germany
• University Hospital Cologne — Cologne, Germany
• Universitaetsklinikum Carl Gustav Carus TU Dresden — Dresden, Germany
• Universitaetsklinikum Erlangen — Erlangen, Germany
• Universitaetsklinikum Essen — Essen, Germany
• Universitaetsklinikum Essen — Essen, Germany
• Universitaetsklinikum Hamburg-Eppendorf — Hamburg, Germany
• Medizinische Hochschule Hannover — Hanover, Germany
• Universitaetsklinikum Heidelberg — Heidelberg, Germany
• Universitaetsklinikum Leipzig AoeR — Leipzig, Germany
• Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz — Mainz, Germany
• Universitaetsklinikum Regensburg — Regensburg, Germany
• Robert-Bosch-Krankenhaus — Stuttgart, Germany
• Nephrologisches Zentrum Villingen-Schwenningen — Villingen-Schwenningen, Germany
• Nierenzentrum Wiesbaden — Wiesbaden, Germany
• Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari — Bari, Italy
• Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi IRCCS — Bologna, Italy
• Azienda Ospedaliero Universitaria di Bologna Policlinico S Orsola Malpighi — Bologna, Italy
• Ospedali Riuniti di Foggia — Foggia, Italy
• Azienda Ospedaliera Universitaria Gaetano Martino — Messina, Italy
• Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico — Milan, Italy
• Ospedale Pediatrico Bambino Gesù — Roma, Italy
• Fondazione Policlinico Universitario Agostino Gemelli IRCCS — Roma, Italy
• Azienda Ospedaliero-Universitaria Santa Maria della Misericordia — Udine, Italy
• King Faisal Specialist Hospital & Research Center — Jeddah, Saudi Arabia
• King Faisal Specialist Hospital & Research Center — Riyadh, Saudi Arabia
• King Fahad Medical City — Riyadh, Saudi Arabia
• Keimyung University Dongsan Hospital — Daegu, South Korea
• Chungnam National University Hospital — Daejeon, South Korea
• Seoul National University Bundang Hospital — Seongnam, South Korea
• Seoul National University Hospital — Seoul, South Korea
• Severance Hospital, Yonsei University Health System — Seoul, South Korea
• Samsung Medical Center — Seoul, South Korea
• The Catholic University of Korea, Seoul St. Mary's Hospital — Seoul, South Korea
• Seoul Metropolitan Government Seoul National University Boramae Medical Center — Seoul, South Korea
• Complejo Hospitalario Universitario A Coruña — A Coruña, Spain
• Hospital Universitari Vall d'Hebron - VHIR — Barcelona, Spain
• Hospital Clinic de Barcelona — Barcelona, Spain
• Hospital Sant Joan de Deu — Barcelona, Spain
• Hospital Universitario de la Palma — Las Palmas, Spain
• Hospital General Universitario Gregorio Marañon — Madrid, Spain
• Hospital Universitario 12 de Octubre — Madrid, Spain
• Hospital La Paz — Madrid, Spain
• Hospital Regional Universitario de Malaga — Málaga, Spain
• Hospital Doctor Peset Valencia — Valencia, Spain
• Hospital Universitari i Politecnic La Fe — Valencia, Spain
• University of Basel — Basel, Switzerland
• Inselspital - University Hospital Bern — Bern, Switzerland
• Hôpitaux Universitaires de Genève - HUG — Geneva, Switzerland
• CHUV, Lausanne University Hospital — Lausanne, Switzerland
• University Hospital Zurich - Children's Hospital Zurich — Zurich, Switzerland
• University Hospital Zurich — Zurich, Switzerland
• Taipei Veterans General Hospital — Taipei, Taiwan
• Cambridge University Hospitals NHS Foundation Trust — Cambridge, United Kingdom
• University Hospital of Wales — Cardiff, United Kingdom
• Royal Hospital for Children — Glasgow, United Kingdom
• Leicester General Hospital — Leicester, United Kingdom
• Royal Free Hospital — London, United Kingdom
• Evelina London Children's Hospital — London, United Kingdom
• Imperial College Healthcare NHS Trust (ICH) — London, United Kingdom
• Royal Manchester Children's Hospital — Manchester, United Kingdom
• Newcastle Hospital NHS Foundation Trust — Newcastle, United Kingdom
• Salford Care Organisation — Salford, United Kingdom