N
← Back to Search
Sponsored

Accelerate Your Clinical Trial Recruitment

Reach thousands of high-intent patients matching your specific inclusion criteria.

Start Campaign
RECRUITING Not applicable ClinicalTrials.gov

ESPB Versus SPSIPB for Quality of Recovery After Video-Assisted Thoracoscopic Surgery

Sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital • ClinicalTrials.gov ID: NCT07729488

Registry updated: 2026-09-21
Ad

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Check Eligibility →

Description

Video-assisted thoracoscopic surgery (VATS) is associated with moderate to severe postoperative pain despite its minimally invasive nature. Ultrasound-guided erector spinae plane block (ESPB) and serratus posterior superior intercostal plane block (SPSIPB) are promising regional analgesic techniques for thoracic surgery; however, evidence directly comparing their effects on postoperative quality of recovery remains limited. This prospective, randomized, double-blind controlled trial aims to compare the effects of ESPB and SPSIPB on postoperative quality of recovery, measured by the Quality of Recovery-15 (QoR-15) questionnaire at 24 hours after surgery. Secondary outcomes include postoperative pain scores, tramadol consumption, time to first rescue analgesia, rescue analgesic requirement, postoperative nausea and vomiting, patient satisfaction, length of hospital stay, block-related complications, and perioperative hemodynamic parameters.

Interventions

  • ESPB (Procedure)
    An ultrasound-guided erector spinae plane block will be performed preoperatively for postoperative analgesia in patients undergoing elective video-assisted thoracoscopic surgery. The block will be performed using the standardized study protocol.
  • SPSIPB (Procedure)
    An ultrasound-guided serratus posterior superior intercostal plane block will be performed preoperatively for postoperative analgesia in patients undergoing elective video-assisted thoracoscopic surgery. The block will be performed using the standardized study protocol.

Eligibility criteria

Inclusion Criteria: * Adults aged 18-85 years. * ASA physical status I-III. * Scheduled for elective VATS under general anesthesia. * Able to understand and complete the QoR-15 questionnaire. * Written informed consent provided. Exclusion Criteria: * Refusal to participate or inability to provide written informed consent. * Known allergy or contraindication to bupivacaine, paracetamol, dexketoprofen, or tramadol. * Infection at the planned block injection site. * Coagulopathy or ongoing anticoagulant therapy precluding regional anesthesia. * Severe hepatic or renal insufficiency. * Chronic opioid use or chronic pain requiring regular analgesic treatment. * Previous thoracic surgery on the operative side. * Pregnancy or breastfeeding. * Cognitive impairment, psychiatric illness, or language barrier preventing completion of the QoR-15 questionnaire. * Body mass index (BMI) \>35 kg/m². * Conversion from VATS to thoracotomy. * Failed or incomplete regional block.

Conditions

Postoperative Pain

Locations

  • Fatma Acil — Diyarbakır, Outside of the US, Turkey (Türkiye)
  • Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital — Diyarbakır, Turkey, Turkey (Türkiye)
Sponsored

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record