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RECRUITING Phase 4 ClinicalTrials.gov

SMILE Surgery in One Eye Compared to Ray Tracing-guided LASIK Surgery in the Fellow Eye

Sponsor: Stanford University • ClinicalTrials.gov ID: NCT07721714

Registry updated: 2026-08-26
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Description

Participants will undergo LASIK surgery in one eye using ray tracing guided technology in one eye and LASIK surgery in the other eye using wavefront guided technology. We are comparing outcomes between the two technologies as measured by self reported quality of vision and quality of life outcomes using validated questionnaires before and after surgery. We will also be comparing outcomes between the two technologies including measurement of low contrast visual acuity,and best spectacle corrected visual acuity.

Interventions

  • Ray tracing guided LASIK surgery (Device)
    LASIK

Eligibility criteria

Inclusion Criteria: Subjects age 22 and older with healthy eyes. Nearsightedness between -1.00 diopters and -8.00 diopters. Subjects with less than or equal to 3.00 diopters of astigmatism. Exclusion Criteria: Subjects under the age of 22. Subjects with excessively thin corneas. Subjects with topographic evidence of keratoconus. Subjects with ectactic eye disorders. Subjects with autoimmune diseases. Subjects who are pregnant or nursing. Subjects must have similar levels of nearsightedness in each eye. They can not be more than 1.5 diopter of difference between eyes. Subjects with more than 3.00 diopters of astigmatism Subjects must have similar levels of astigmatism in each eye. They can not have more than 0.75 diopters of difference between eyes.

Conditions

Myopia Astigmatism

Locations

  • Byers Eye Institute — Palo Alto, California, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record