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RECRUITING Not applicable ClinicalTrials.gov

LASER VERSUS CRYSTALLIZED PHENOL IN PILONIDAL SINUS DISEASE

Sponsor: Sanliurfa Education and Research Hospital • ClinicalTrials.gov ID: NCT07701772

Registry updated: 2026-09-01
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Description

This single-center prospective randomized parallel-group trial compares laser ablation and crystallized phenol application in adults with primary uncomplicated sacrococcygeal pilonidal sinus disease. The primary objective is to compare postoperative day 1 pain intensity between the two treatment methods. Secondary objectives include complete epithelialization by day 30, time to complete epithelialization, postoperative day 7 pain, duration of analgesic use, time to return to daily activities and work, early local complications, and 6-month recurrence.

Interventions

  • Laser Ablation (Procedure)
    After a small incision, hair and debris removal, and curettage, laser ablation is performed using a Leonardo Mini 1470 nm diode laser.
  • Crystallized phenol application (Procedure)
    After a small incision, hair and debris removal, and curettage, crystallized phenol is applied to the sinus cavity.

Eligibility criteria

Inclusion Criteria: * Age 18 years or older * Diagnosis of primary chronic sacrococcygeal pilonidal sinus disease * Uncomplicated disease * Suitability for minimally invasive treatment * Provision of written informed consent Exclusion Criteria: * Acute pilonidal abscess * History of pilonidal abscess drainage * Previous surgical or interventional treatment for pilonidal sinus disease * Recurrent pilonidal disease * Complex pilonidal disease or marked lateral extension * Immunosuppression, chronic steroid use, or systemic conditions that may significantly impair wound healing * Inability to attend regular follow-up * Refusal to participate in the study

Conditions

Sacrococcygeal Pilonidal Sinus Disease Pilonidal Sinus Disease

Locations

  • Sanliurfa Education and Research Hospital — Sanliurfa, Şanlıurfa, Turkey (Türkiye)
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record