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RECRUITING Not applicable ClinicalTrials.gov

Electronic Health Record Augmented LDL-Cholesterol Optimization and Control Via Active Lipid Engagement (EHR-LOCALE): A Quality Improvement Implementation Study

Sponsor: University of Alberta • ClinicalTrials.gov ID: NCT07685639

Registry updated: 2026-09-09
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Description

The purpose of this study is to determine whether a proactive, EHR-guided approach helps more individuals reach safe cholesterol levels, improves medication use, and reduces future heart attacks and strokes, compared to usual care. The main question it aims to answer is: • Does the EHR-LOCALE pathway increases the proportion of patients who reach the LDL-cholesterol target of \<1.8 mmol/L at 6 months? Participants in the interventional group receive: * Pharmacist contact * Repeat lipid requisitions * Review of medications, adherence, and side effects * Treatment escalation according to national dyslipidemia guidelines

Interventions

  • Pharmacist-led lipid optimization pathway (Other)
    Referral to a centralized, pharmacist-led, telephone clinic for optimization of dyslipidemia management

Eligibility criteria

Inclusion Criteria: 1. Adults over the age of 18 2. Resident of Alberta 3. Individuals hospitalized with an acute coronary syndrome and have undergone coronary angiography. 4. Able to participate in follow-up contact if randomized to the intervention arm Exclusion Criteria: 1\. In-hospital mortality

Conditions

ACS (Acute Coronary Syndrome) Hyperlipidemia Dyslipidemia Low-Density-Lipoprotein-cholesterol Level

Locations

  • University of Alberta Hospital / Mazankowski Alberta Heart Institute — Edmonton, Alberta, Canada
  • University of Alberta Hospital / Mazankowski Alberta Heart Institute — Edmonton, Alberta, Canada
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record