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RECRUITING Not applicable ClinicalTrials.gov

Interventions to Enhance Quadriceps Output After ACLR

Sponsor: University of Wisconsin, Madison • ClinicalTrials.gov ID: NCT07674784

Registry updated: 2026-10-01
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Description

The investigators are interested in determining what treatments are effective in reducing inhibition after anterior cruciate ligament (ACL) surgery and helping people increase quadriceps strength. Two interventions that are often used clinically are neuromuscular electrical stimulation (NMES) and vibration. This is a study of how effective these treatments are, whether they work the same for everyone, and if one is better than the other. 22 participants will be enrolled and on study for 2 to 3 weeks.

Interventions

  • NMES (Device)
    The thigh of the surgical leg will be cleaned with isopropyl alcohol. 2.75" x 5" NMES electrodes (Dura-Stick Plus, Chattanooga, DJO Global, Dallas, TX) will be adhered to the proximal and distal aspects of the quadriceps muscles. An FDA-approved portable neuromuscular electrical stimulator (Empi Continuum, DJO Global, Dallas, TX) will be utilized to deliver a biphasic square wave pulse (frequency 75 Hz, pulse width 300 µs) to the quadriceps of the surgical limb. Participants will control both the amplitude of current delivered (0-100 mA) and the on/off timing of the stimulation via a wired control switch. Participants will complete common post-ACLR rehabilitation exercises while NMES is delivered (total time for exercises is approximately 20 minutes).
  • Vibration (Device)
    Participants will sit in a comfortable position on a treatment plinth with knees flexed to \~30°, hips flexed between 30-60°, and the back supported. The back of the thighs will rest on the vibration pads of a commercial vibration device (Thumper Versa Pro Massager, (Thumper Massager Inc., Markham, Ontario, CA). Participants will sit at rest for 20 minutes while the vibration device provides a 30 Hz vibration with an amplitude of \~6 mm.

Eligibility criteria

Inclusion Criteria: * Have undergone ACLR within the previous 4 months * Are at least 2 months post-ACLR Exclusion Criteria: * A history of ACLR on both legs * Since the most recent ACLR: * secondary lower extremity surgery * leg or foot fracture * Unable to walk without an assistive device * Pain of greater than 5/10 during quadriceps strengthening exercises with the surgical limb * Cannot achieve 90 degrees of knee flexion with the surgical limb * People with contraindications to NMES * Anyone who had a previous skin reaction to NMES or attempted but could not tolerate NMES * Peripheral neuropathy or other neurological conditions

Conditions

ACL

Locations

  • UW Health — Madison, Wisconsin, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record