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RECRUITING Not applicable ClinicalTrials.gov

Feasibility of a Community-Integrated Isometric Handgrip Exercise Program and Its Preliminary Effects on Blood Pressure and Cognitive Function in Older Adults

Sponsor: McMaster University • ClinicalTrials.gov ID: NCT07648498

Registry updated: 2026-10-07
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Description

The goal of this clinical trial is to evaluate whether a short, supervised isometric handgrip exercise program is feasible and acceptable for older adults with elevated blood pressure or hypertension. It will also explore whether this type of exercise may improve blood pressure and cognitive function. The main questions it aims to answer are: * Is this handgrip exercise program practical and acceptable for older adults to participate in within a community exercise setting? * Does participation in the program lead to changes in blood pressure and cognitive function? Researchers will compare two handgrip devices to determine whether the method of delivering the exercise influences feasibility and outcomes. Participants will: * Be randomly assigned to use one of two handgrip devices. * Complete supervised exercise sessions twice per week for 4 weeks. * Perform brief handgrip contractions at a set intensity during each session. * Complete blood pressure and cognitive assessments before and after the program.

Interventions

  • Zona Plus 4-Week Isometric Handgrip Exercise Intervention (Other)
    This intervention consists of a supervised, low-dose isometric handgrip exercise program delivered over 4 weeks using the Zona Plus handgrip dynamometer. Participants will complete two sessions per week, each consisting of 4x2-minute isometric handgrip contractions performed at 30% of maximal voluntary contraction, with 1-minute rest periods between contractions. Contractions will be performed using alternating hands. All sessions will be conducted in person and supervised by trained research staff at the Physical Activity Centre of Excellence, and the intervention will completed before participants' existing exercise routines. Ratings of perceived exertion will be recorded following each contraction.
  • Squegg 4-Week Isometric Handgrip Exercise Intervention (Other)
    This intervention consists of a supervised, low-dose isometric handgrip exercise program delivered over 4 weeks using the Squegg handgrip device. Participants will complete two sessions per week, each consisting of 4x2-minute isometric handgrip contractions performed at 30% of maximal voluntary contraction, with 1-minute rest periods between contractions. Contractions will be performed using alternating hands. All sessions will be conducted in person and supervised by trained research staff at the Physical Activity Centre of Excellence, and the intervention will completed before participants' existing exercise routines. Ratings of perceived exertion will be recorded following each contraction.

Eligibility criteria

Inclusion Criteria: * 65 years of age or older * Currently attending the Physical Activity Centre of Excellence at McMaster University * English speaking * Diagnosed with hypertension or elevated blood pressure Exclusion Criteria: * Current or prior participation in chronic isometric exercise * Unstable angina. * Uncontrolled hypertension * Uncontrolled heart failure and/or arrhythmias * Recent myocardial infarction or electrocardiography changes * Complete heart block * Carpal tunnel syndrome * Arthritis that may be aggravated by handgrip exercise * Changes to the type and/or dose of blood pressure medications within 3 months of starting the study.

Conditions

Hypertension Elevated Blood Pressure

Locations

  • NeuroFit Lab, Ivor Wynne Centre, McMaster University — Hamilton, Ontario, Canada
  • Physical Activity Centre of Excellence, Ivor Wynne Centre, McMaster University — Hamilton, Ontario, Canada
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record