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RECRUITING Not applicable ClinicalTrials.gov

Feasibility, Usability, and Acceptability of Virtual Reality-Based Cognitive and Physical Rehabilitation in Individuals With Mild Cognitive Impairment

Sponsor: The University of Texas Health Science Center, Houston • ClinicalTrials.gov ID: NCT07638748

Registry updated: 2026-09-02
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Description

The purpose of this study is to demonstrate feasibility, usability, and acceptability of virtual reality (VR)-based cognitive and physical rehabilitation, evaluate adherence, tolerability, and fidelity to the VR intervention and explore preliminary effectiveness of VR-based rehabilitation on cognitive, physical, and functional outcomes.

Interventions

  • Virtual Reality (VR) sessions (Device)
    Participants will complete 3 supervised virtual reality (VR) sessions per week for 6 weeks for a total of 18 sessions using either the Real System VR headset or the Oculus Quest 2 VR headset. Each session will last approximately 60 minutes, with time allocated for setup and brief symptom checks.

Eligibility criteria

Inclusion Criteria: * Clinical diagnosis of MCI (MoCA 18-26) or self-reported subjective cognitive decline (SCD) * Capacity to provide informed consent * Able to provide own transportation to sessions * Speaks and understands English * Ambulatory Exclusion Criteria: * Uncontrolled seizures or epilepsy * Severe psychiatric illness or active suicidality * Inability to follow instructions or tolerate VR (severe motion sickness) * Cognitive impairment as a result of a known cause (e.g., dementia, stroke, Traumatic Brain Injury (TBI), medications, etc.) * Any condition that the research team determines would interfere with safe participation

Conditions

Mild Cognitive Impairment Subjective Cognitive Decline (SCD)

Locations

  • The University of Texas Health Science Center at Houston — Houston, Texas, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record