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RECRUITING Not applicable ClinicalTrials.gov

Home-based Vision Rehabilitation Guided by Brain Imaging

Sponsor: Georgetown University • ClinicalTrials.gov ID: NCT07635329

Registry updated: 2026-09-14
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Description

The BRIGHT (Behavioral Rehabilitation Through Image-Guided Home-based Training) study aims to evaluate the effectiveness of image-guided, home-based perceptual training at improving visual performance in individuals with visual field loss. Using a prospective, crossover design, BRIGHT combines visual behavioral testing, neuroimaging, and a home-based intervention. It aims to 1) identify neural pathways that support training-induced visual plasticity; and 2) compare the efficacy of different types of visual training delivered in a home-based setting.

Interventions

  • High-level perceptual learning-based training (Behavioral)
    Behavioral intervention consisting of repeated computerized visual discrimination tasks targeting higher-order visual processing
  • Low-level perceptual learning-based training (Behavioral)
    behavioral intervention consisting of repeated computerized visual discrimination tasks targeting low-level visual processing

Eligibility criteria

Inclusion Criteria: 1. At least 18 years of age. 2. Capable of providing informed consent and complying with study procedures. 3. Unilateral or bilateral focal brain damage causing visual field loss. 4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year. 5. Eligible for MRI based on standard safety screening. Exclusion Criteria: 1. Severe neurological or psychiatric conditions unrelated to the focal lesion that may interfere with study participation or data interpretation. 2. Current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5. 3. Ocular disease or disorder.

Conditions

Visual Field Defect Stroke Hemianopia Homonymous Quadrantanopia Cortical Blindness Visual Field Defect, Peripheral Visual Field Loss Traumatic Brain Injury Brain Tumor

Locations

  • Georgetown University Medical Center — Washington D.C., District of Columbia, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record