An Extension Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer in China
Sponsor: Genmab • ClinicalTrials.gov ID: NCT07604766
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The purpose of this Chinese extension study is to compare how well Rina-S works against platinum-resistant ovarian cancer compared to chemotherapy drugs that are already approved and used for platinum-resistant ovarian cancer. Treatment in this study could be Rina-S or it could be 1 of 4 indicated chemotherapy agents that are considered standard medical care. There is an equal (50:50) chance of getting Rina-S or an approved chemotherapy agent as treatment in this study. No one will know what treatment they are assigned to until the first dose. All participants will receive active drug; no one will be given placebo. This study is an extension study of the protocol GCT1184-02 (NCT06619236).
Interventions
-
Rina-S
(Drug)
Intravenous (IV) infusion
-
Paclitaxel
(Drug)
IV infusion
-
Topotecan
(Drug)
IV infusion
-
Pegylated liposomal doxorubicin (PLD)
(Drug)
IV infusion
-
Gemcitabine
(Drug)
IV infusion
Eligibility criteria
Conditions
Locations
- The First Hospital of Jilin University — Changchun, China
- Hunan Cancer Hospital — Changsha, China
- West China Second University Hospital, Sichuan University — Chengdu, China
- Chongqing University Cancer Hospital - Chongqing Cancer Hospital — Chongqing, China
- Sun Yat-Sen Memorial Hospital — Guangzhou, China
- Sun Yat-Sen University Cancer Center — Guangzhou, China
- Zhejiang Cancer Hospital — Hangzhou, China
- Harbin Medical University Cancer Hospital — Harbin, China
- Shandong First Medical University Affiliated Tumor Hospital — Jinan, China
- Nanjing Drum Tower Hospital (The Affiliated Hospital of Nanjing University Medical School) — Nanjing, China
- Fudan University Shanghai Cancer Hospital — Shanghai, China
- Obstetrics & Gynecology Hospital of Fudan University — Shanghai, China
- Liaoning Cancer Hospital — Shenyang, China
- Shanxi Cancer Hospital — Taiyuan, China
- Tianjin Medical University Cancer Institute & Hospital — Tianjin, China
- The First Affiliated Hospital of Xi'an Jiaotong University — Xi'an, China
- Henan Cancer Hospital — Zhengzhou, China
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Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
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