N
← Back to Search
Sponsored

Accelerate Your Clinical Trial Recruitment

Reach thousands of high-intent patients matching your specific inclusion criteria.

Start Campaign
RECRUITING Not applicable ClinicalTrials.gov

Ultrasound-Guided Rectus Sheath Block Versus Local Infiltration

Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • ClinicalTrials.gov ID: NCT07582029

Registry updated: 2026-10-16
Ad

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Check Eligibility →

Description

Laparoscopic cholecystectomy is associated with significant postoperative pain originating from trocar sites, pneumoperitoneum, and visceral irritation. Both local anesthetic infiltration and ultrasound-guided rectus sheath block are commonly used regional analgesic techniques to reduce postoperative pain and opioid consumption. This prospective randomized controlled study aims to compare the effects of these two techniques on postoperative pain scores, opioid requirements, and analgesia-related adverse effects following laparoscopic cholecystectomy.

Interventions

  • Rectus Sheath Block (Procedure)
    After completion of the operation, during the surgical closure phase, bilateral rectus sheath block will be performed. A linear ultrasound probe will be placed transversely over the umbilicus and 1 cm lateral to it. After visualization of the rectus abdominis muscle and posterior rectus sheath, a 22-Gauge 80 mm block needle (Braun Stimuplex Ultra-360, Melsungen, Germany) will be advanced from lateral to medial using the in-plane technique. Following hydrodissection with 1 mL saline between the rectus muscle and posterior sheath and confirmation of appropriate spread, 20 mL local anesthetic (0.25% bupivacaine) will be administered with intermittent negative aspiration.
  • Local Anesthetic Infiltration (Procedure)
    At the end of the operation, the surgeon will infiltrate 5 mL local anesthetic (0.5% bupivacaine) subcutaneously into each of the four trocar insertion sites.

Eligibility criteria

Inclusion Criteria: * ASA (American Society of Anesthesiologists) class I-II patients * Patients aged between 18 and 65 years * Patients undergoing laparoscopic cholecystectomy surgery Exclusion Criteria: * ASA class III-IV patients * Patients undergoing emergency surgery * Relatives of patients who do not provide consent * Presence of chronic pain * Chronic opioid use * Presence of local anesthetic allergy * Ibuprofen allergy * Paracetamol allergy * Presence of infection at the block site * Coagulopathy * Increased intracranial pressure * Pre-existing neurological deficit * Severe organ failure * Mental retardation * Anatomical deformity

Conditions

Cholelithiases Cholecystitis Postoperative Pain

Locations

  • Sisli Hamidiye Etfal Training Hospital — Istanbul, Turkey (Türkiye)
Sponsored

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record