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RECRUITING Not applicable ClinicalTrials.gov

The Effect of Resistance Exercise in Patients With Lower Limb Lymphedema (the LymphEx Study)

Sponsor: Carsten Bogh Juhl • ClinicalTrials.gov ID: NCT07558317

Registry updated: 2026-09-18
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Description

The aim of the study is to investigate the short-term (within 2 weeks) effects of resistance exercise with and without compression garments on lower limb lymphedema(LLL). Additionally, the study will explore the immediate response in LLL to resistance exercise (2 hours and 24 hours post-exercise). Participants will continously wear a circumfencential sensor at the calf (CIMON from Icompression) under a compression garment and an activity tracker (SENS Motion from SENS Innovation Aps) at the thigh for 3 periods (two with supervised exercise sessions of 2 weeks and one control period). Participants will attend supervised resistance exercise 2-3 times per week for 2 periods of 2 weeks (one with compression garment and one without). Assessments with the principal investigator will be scheduled before and after every 2 week period. Participants will keep a digital diary or diary in paper of their lymphedema related symptoms and experienced issues with the sensors or app.

Interventions

  • Resistance exercise (Other)
    Supervised resistance exercise targeted at the larger muscle groups in the lower limbs, 5 exercises, 3 sets of 10RM

Eligibility criteria

Inclusion Criteria: * verified diagnosis of lymphedema of the lower limb * completed compression bandaging * adherence to compression garment in daytime (minumum 5-6 days per week) * calf circumference \> 35 and \<75 cm Exclusion Criteria: * severe neuropathy of the lower leg * severe skin problems or wounds at the lower leg * cellulitis, DVT or acute injuries of the lower limb \< 2 months prior to inclusion * ongoing adjuvant treatment for cancer

Conditions

Lymphedema

Locations

  • Herlev and Gentofte Hospital, Department of Physiotherapy and Occupational Therapy — Herlev, Denmark
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record