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RECRUITING Not applicable ClinicalTrials.gov

Preoperative Oncogeriatric Assessment in Patients Undergoing Hepatectomy

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • ClinicalTrials.gov ID: NCT07537569

Registry updated: 2026-09-10
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Description

This study aims to bridge the gap between geriatric medicine and surgical oncology. The findings will provide valuable insights into optimizing perioperative care for older adults, enhancing surgical safety, and improving long-term recovery trajectories, thereby supporting a more patient-centered, multidisciplinary approach in the management of elderly patients undergoing hepatectomy

Interventions

  • Comprehensive Geriatric Assessment (CGA) (Other)
    The Comprehensive Geriatric Assessment (CGA) is conducted using a structured approach integrating validated tools into routine preoperative evaluation: frailty assessed by Fried Frailty Criteria; functional status by Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL); cognitive function by Mini-Mental State Examination (MMSE) or Montreal Cognitive Assessment (MoCA); comorbidity burden by Charlson Comorbidity Index; nutritional status by Mini Nutritional Assessment (MNA); psychological status by Geriatric Depression Scale (GDS). Based on CGA findings, participants may receive individualized preoperative interventions including nutritional optimization, physical prehabilitation, medical optimization, and psychosocial or educational support.

Eligibility criteria

Inclusion Criteria: * Patients aged ≥ 70 years * Diagnosed hepatic malignancies requiring hepatectomy * Eligible for curative surgery as determined by multidisciplinary team * Ability to provide informed consent. Exclusion Criteria: * Ineligibility for surgery due to advanced disease or severe comorbidities * Severe cognitive impairment (MMSE score \< 18) * Refusal to participate

Conditions

Hepatic Malignancies Comprehensive Geriatric Assessment Hepatectomy

Locations

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS — Roma, RM, Italy
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record