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RECRUITING Not applicable ClinicalTrials.gov

Photobiomodulation Effects on Blood Pressure and Vascular Function in Treated Hypertensive Patients

Sponsor: University of Nove de Julho • ClinicalTrials.gov ID: NCT07525310

Registry updated: 2026-09-09
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Description

This double-blind, randomized, sham-controlled clinical trial aims to evaluate the effects of vascular photobiomodulation on blood pressure and vascular function in hypertensive patients treated with losartan. A total of 80 patients using losartan (100 mg/day for at least two months) will be recruited and followed for 4 weeks. Participants will be randomly allocated to either an active photobiomodulation group or a sham control group.

Interventions

  • Vascular Photobiomodulation (Device)
    Vascular photobiomodulation therapy applied over the radial artery using a red laser (wavelength: 660 nm; power: 100 mW).
  • Sham Photobiomodulation (Device)
    Laser emission will be blocked to ensure no therapeutic effect

Eligibility criteria

Inclusion Criteria: * Be taking losartan at a dose of 100 mg/day, either as monotherapy or in combination with other antihypertensive medications, administered in two divided doses, for a minimum of 2 months and a maximum of 24 months. * Present systolic blood pressure is less than or equal to 140 mmHg and diastolic less than or equal to 90 mmHg. * Not having used any other antihypertensive medication in the last 2 months. * Age between 18 and 65 years * If female, not pregnant * No cutaneous/subcutaneous lesions on both arms. * No musculoskeletal, rheumatic, cardiovascular, metabolic, neurological, oncological, immunological, hematological, psychiatric or cognitive diagnoses and that may be worsened by the intervention or prevent the correct application of FBM vascular. Exclusion Criteria: * Changes in medication status during the study

Conditions

Hypertension

Locations

  • Raphael Dias — São Paulo, São Paulo, Brazil
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record