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RECRUITING Not applicable ClinicalTrials.gov

Contamination of Young Children Hair During Acute Cannabis Intoxication

Sponsor: University Hospital, Toulouse • ClinicalTrials.gov ID: NCT07524088

Registry updated: 2026-09-21
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Description

Hair analysis in pediatric cannabis intoxication is limited by possible sudoral self-contamination, especially in young children due to hair porosity. However, adult studies show no THC-COOH in sweat, challenging this hypothesis. THC-COOH presence in sweat has to this day never been studied in young children. Its absence would help assess the reliability of hair testing for prior exposure. Thus, our main objective is to describe whether THC-COOH can be detected in sweat following cannabis intoxication using gold standard techniques.

Interventions

  • sudoral and hairing sampling (Other)
    Sweat sampling using the "sweat test" method, performed after skin stimulation with pilocarpine and a low electrical stimulation. Hair sampling during the follow-up consultation. Sweat, and capillary assays of THC and its main metabolites

Eligibility criteria

Inclusion Criteria: * Child admitted to the Specialized Emergency Pole (POSU) and pediatric medico-surgical emergencies for acute cannabis intoxication. * Child older than 3 months and younger than 3 years. * Holders of parental authority, affiliated with or beneficiaries of a social security system. Exclusion Criteria: * History of cannabis intoxication identified during the interview and/or consultation of the medical record. * Contraindication to sweat sampling (described in section 6). * Absence of hair and/or hair length \< 1 cm at the time of inclusion. * Ongoing breastfeeding (exclusive and mixed). * Inability to provide study-related informations to the holders of parental authority.

Conditions

Cannabis Intoxication in Children

Locations

  • Centre Hospitalier Universitaire — Toulouse, France
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record