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RECRUITING Not applicable ClinicalTrials.gov

The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis

Sponsor: University of Illinois at Chicago • ClinicalTrials.gov ID: NCT07504120

Registry updated: 2026-10-06
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Description

Objectives Objective 1: To determine the effects of a 16-week remotely delivered Pilates intervention on walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS. Objective 2: To examine the impact of a 16-week remotely delivered Pilates intervention on depression \& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS. Aim Aim 1: To assess whether the 16-week remotely delivered Pilates intervention significantly improves walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS Aim 2: To investigate whether the 16-week remotely delivered Pilates intervention significantly improves depression \& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS. Hypothesis Hypothesis 1: The 16-week remotely delivered Pilates intervention will significantly improve walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS. Hypothesis 2: Participants receiving the 16-week remotely delivered Pilates intervention will demonstrate significantly greater improvements in depression \& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS.

Interventions

  • Pilates (Behavioral)
    REMOTLY PILATES EXERCISE

Eligibility criteria

Inclusion Criteria: * Age 18 years or older * Self-reported diagnosis of multiple sclerosis by a neurologist * Relapse-free for the past 30 days before screening * Able to speak and read English as the primary language * Access to the internet and e-mail, * Ability to use Zoom, and willingness to complete testing sessions and questionnaires * Ambulatory without an assistive device (for example, cane) * Low to moderate disability, defined as a score of 0-4 on the Patient-Determined Disease Steps (PDDS) * Insufficiently active, defined as a score \< 14 on the Godin Leisure-Time Exercise Questionnaire-Health Contribution Score (GLTEQ-HCS) * Adequate visual ability and literacy to read materials printed in 14-point font * Currently treated with a disease-modifying therapy Exclusion Criteria: * Pregnant * Elevated risk for strenuous or maximal exercise, defined as more than one "Yes" response on the Physical Activity Readiness Questionnaire (PAR-Q) during screening

Conditions

Multiple Sclerosis Pilates Exercise Walking Balance Fatigue in Multiple Sclerosis Pain Management Quality of Life Depression Cognition Fatigue

Locations

  • University of Illinois Chicago — Chicago, Illinois, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record