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Effects of Post-Isometric Relaxation and Myofascial Release on Low Back Pain With Lower Cross Syndrome

Sponsor: University of Karachi • ClinicalTrials.gov ID: NCT07496099

Registry updated: 2026-08-28

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Description

This randomized controlled trial aims to evaluate the combined effects of post-isometric relaxation and myofascial release on pain, flexibility, and functional disability in individuals with low back pain associated with lower cross syndrome. Eligible participants aged 18 to 45 years will be randomly allocated into two parallel intervention groups. One group will receive post-isometric relaxation combined with myofascial release, while the comparison group will receive conventional stretching combined with Therapeutic modalities. Outcomes will be assessed at baseline and after completion of the intervention period. The results of this study are expected to contribute to evidence-based physiotherapy management of low back pain associated with postural imbalance.

Interventions

post isometric relaxation (Other)
Post-isometric relaxation will be applied to the hamstring muscles. Participants will be positioned supine with the hip flexed to 90 degrees and will perform a submaximal isometric contraction of the hamstrings against therapist resistance for 5 to 8 seconds, followed by a passive stretch of approximately 10 seconds. The procedure will be repeated three times per limb per session.
MYOFASCIAL RELEASE (Other)
Myofascial release will be applied to the hamstring muscles with the participant in a prone position. Sustained manual pressure will be applied along the length of the hamstring muscles using the therapist's hands for approximately 30 seconds per application, repeated multiple times per session to improve tissue extensibility.
Conventional Static Stretching (Other)
Conventional static stretching of the hamstring muscles will be performed with the participant in a supine position. Each stretch will be held for approximately 30 seconds and repeated three times per limb per session as part of routine physiotherapy management.
Therapeutic Modalities (Other)
Therapeutic modalities, including ultrasound therapy or superficial heat application using a heating pad, will be applied prior to stretching to reduce pain and improve tissue extensibility as part of conventional physiotherapy care.

Eligibility criteria

Inclusion Criteria: 1. Participants aged 18-45 years old 2. having low back pain persisting for at least 4 weeks 3. with clinical diagnosis of LCS, and hamstring tightness (AKE \>15°) Exclusion Criteria: 1. Participants with the history of spinal surgery active neurological conditions 2. systemic disease affecting connective tissue (Rheumatoid arthritis, Systemic lupus erythematosus) 3. recent lower limb or spinal injury (within 6 months) 4. pregnancy or inability to lie prone for treatment.

Conditions

Low Back Pain, Mechanical Lower Cross Syndrome Hamstring Muscle Tightness

Locations

life cure physiotherapy clinic malir cantt, Karachi — Karachi, Sindh, Pakistan

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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