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RECRUITING Not applicable ClinicalTrials.gov

Tetris Intervention Following Subliminal Reactivation for Intrusive Memories

Sponsor: Shaanxi Normal University • ClinicalTrials.gov ID: NCT07495917

Registry updated: 2026-09-02
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Description

Intrusive memories of traumatic events are a core feature of Post-Traumatic Stress Disorder (PTSD) and can cause substantial distress and functional impairment. Existing trauma-focused treatments are effective but often require deliberate recollection of traumatic experiences, which can be distressing for some individuals. Previous experimental studies in healthy participants found that masked reactivation of trauma-related cues, followed after a brief interval by a visuospatial interference task using Tetris gameplay, reduced the frequency and emotional intensity of intrusive memories. Building on these findings, the present randomized controlled trial evaluates the efficacy of this intervention in trauma-exposed individuals experiencing three or more intrusive memories per week.

Interventions

  • Subliminal Reactivation Followed by Visuospatial Interference (Behavioral)
    In each intervention session, participants are exposed subliminally to trauma-related cues. Participants then complete a 10-minute music-listening task during the post-reactivation interval, followed by a computerized visuospatial interference task (Tetris) with mental rotation instructions.
  • Computer-based Visuospatial Task (Tetris) (Behavioral)
    A computerized visuospatial task (Tetris) with mental rotation instructions.

Eligibility criteria

Inclusion Criteria: 1. Meet DSM-5 PTSD Criterion A (eg, exposure to actual or threatened death). Have experienced one or more traumatic events. 2. Experienced three or more intrusive memories during the baseline week. 3. Have internet access and have access to a personal computer. 4. Be willing to provide consent and able to complete study procedures and be contacted by the study team. Exclusion Criteria: 1. Have fewer than three intrusive memories during the baseline week. 2. A current diagnosis of schizophrenia, obsessive-compulsive disorder (OCD), a severe personality disorder judged to interfere with treatment adherence, or acute suicidal behavior. 3. Have severe substance dependence.

Conditions

Post-traumatic Stress Disorder (PTSD) Intrusive Memories of Traumatic Event(s)

Locations

  • School of Psychology, Shaanxi Normal University — Xi'an, Shaanxi, China
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record