RECRUITING Not applicable ClinicalTrials.gov

Lifestyle Change Implementation Research Network at PRC at UMass Chan

Sponsor: University of Massachusetts, Worcester • ClinicalTrials.gov ID: NCT07481305

Registry updated: 2026-09-24

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Description

The goal of this project is to study how well the Noom digital lifestyle program works for adults who are taking Glucagon-Like Peptide-1 receptor agonist (GLP-1) medications. The study team will assess how the program affects people's behaviors and health outcomes. The team will also look at how digital lifestyle change interventions can be implemented in real-world settings, including how many people it reaches, how well it is put into practice, whether people stick with it over time, and whether it works well for different groups of people.

Interventions

Digital Lifestyle Coaching Program (Other)
Participants will be enrolled for a 4-month program, in which they will use the Noom app to self-monitor their dietary intake/physical activity, be provided with coaching feedback throughout, and access educational module. Modules include behavior change specific to GLP-1, i.e. higher protein intake than what is prescribed in Noom Weight, Common challenges while taking GLP-1 medications, and weight loss medications and what to expect while taking them. They will also have access to the Muscle Defense program, which provides education on resistance training exercises to prevent muscle loss.

Eligibility criteria

Inclusion Criteria: 1. Began using a GLP-1 within the past 6 months 2. Currently using GLP-1 3. Plans to continue GLP-1 use 4. GLP-1 prescribed by their physician (e.g., not online or 3rd party vendor) 5. BMI ≥27 kg/m2 6. Age 18 years of age and older 7. Speaks and reads English or Spanish 8. Willing to enroll in a digital lifestyle intervention for 4-months 9. Willing to wear a Fitbit for 8 months Exclusion Criteria: 1. Was taking a GLP-1 within the 2 months prior to the current GLP-1 start date 2. Currently participating in a structured lifestyle change program (receiving structured guidance and counseling on physical activity, diet or weight loss) 3. Currently pregnant 4. Planning to become pregnant in the next year 5. Active diagnosis of an eating disorder 6. Active diagnosis of Schizophrenia or bipolar disorder 7. Unable to walk without assistance/assistive device or have restricted walking 8. Inability to understand the study and provide informed consent 9. Any physical, cognitive, or psychiatric condition that poses a risk or interferes with their ability to participate at the discretion of the study PI (Co-Is: in consultation with PI or if acting as/standing in for PI)

Conditions

GLP - 1

Locations

UMass Chan Medical School - Shaw Building — Worcester, Massachusetts, United States

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record

Accelerate Your Clinical Trial Recruitment