N
← Back to Search
Sponsored

Accelerate Your Clinical Trial Recruitment

Reach thousands of high-intent patients matching your specific inclusion criteria.

Start Campaign
RECRUITING Phase 2 ClinicalTrials.gov

A Study of Brenipatide in Adult Participants With Schizophrenia

Sponsor: Eli Lilly and Company • ClinicalTrials.gov ID: NCT07410507

Registry updated: 2026-10-07
Ad

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Check Eligibility →

Description

The purpose of this study is to assess the efficacy and safety of brenipatide when administered with standard of care (SoC) compared to placebo plus SoC for treatment of schizophrenia. The trial is divided into three periods as follows: Screening period will last approximately 1 month, treatment period will last a maximum of 12 months, and the follow up period will last approximately 2 months. The length of time of your study participation may last up to approximately 15 months.

Interventions

  • Brenipatide (Drug)
    Administered SC
  • Placebo (Drug)
    Administered SC

Eligibility criteria

Inclusion Criteria: * Meet the diagnostic criteria of schizophrenia * Are on a stable standard of care medication regimen for schizophrenia * If the duration of illness is \>6 years, participant has experienced at least one relapse of schizophrenia in last 3 years * Have at least 1 reliable study partner (for example, a family member, social worker, caseworker, residential facility staff, or nurse) * Are reliable and willing to make themselves available for the duration of the study and attend required study visits, and are willing and able to follow study procedures as required, such as * self-inject study intervention store and use the provided study intervention as directed, * maintain electronic or paper study diaries, as applicable, and * complete the required questionnaires Exclusion Criteria: * Have lifetime history of bipolar disorder, borderline personality disorder, or any eating disorder * Evidence of moderate or severe substance or alcohol use disorder within 180 days of screening * Have type 1 diabetes, or history of ketoacidosis or hyperosmolar state or coma * Are actively suicidal or deemed to be a significant risk for suicide * Are currently enrolled in any other clinical study involving an investigational product or any other type of medical research judged not to be scientifically or medically compatible with this study

Conditions

Schizophrenia

Locations

  • Pillar Clinical Research- Little Rock — Little Rock, Arkansas, United States
  • Clinical Innovations, Inc. dba CITrials — Bellflower, California, United States
  • Collaborative Neuroscience Research, LLC — Garden Grove, California, United States
  • Catalina Research Institute, LLC — Montclair, California, United States
  • Stanford University School of Medicine — Stanford, California, United States
  • Collaborative Neuroscience Research, LLC — Torrance, California, United States
  • Sunwise Clinical Research — Walnut Creek, California, United States
  • Institute of Living — Hartford, Connecticut, United States
  • Yale University School of Medicine — New Haven, Connecticut, United States
  • Magno Medical Research Group — Cooper City, Florida, United States
  • NextPhase Research Florida - Hollywood — Hollywood, Florida, United States
  • Innovative Clinical Research — Lauderhill, Florida, United States
  • Accel Research Sites - Maitland Clinical Research Unit — Maitland, Florida, United States
  • Wellness Research Center — Miami, Florida, United States
  • Vital Medical Research — Miami, Florida, United States
  • CLA Research — Naples, Florida, United States
  • Apg Research, Llc — Orlando, Florida, United States
  • Atlanta Center for Medical Research — Atlanta, Georgia, United States
  • Augusta University — Augusta, Georgia, United States
  • Re:Cognition Health - Chicago — Chicago, Illinois, United States
  • CBH Health — Gaithersburg, Maryland, United States
  • McLean Hospital — Belmont, Massachusetts, United States
  • Adams Clinical Watertown — Watertown, Massachusetts, United States
  • University of Massachusetts Chan Medical School — Worcester, Massachusetts, United States
  • Arch Clinical Trials — St Louis, Missouri, United States
  • Adams Clinical Harlem — New York, New York, United States
  • Insight Clinical Trials — Independence, Ohio, United States
  • University of Oregon — Eugene, Oregon, United States
  • Adams Clinical Philadelphia — Philadelphia, Pennsylvania, United States
  • Adams Clinical Dallas — DeSoto, Texas, United States
  • Re:Cognition Health - Fort Worth — Fort Worth, Texas, United States
  • Northwest Clinical Research Center — Bellevue, Washington, United States
  • Centro Neurobiológico y de Estrés Traumático (CENydET) — Buenos Aires, Argentina
  • Fundación para el Estudio y Tratamiento de Enfermedades Mentales (FETEM) — Buenos Aires, Argentina
  • Instituto Nacional de Psicopatología (INAPsi)- FunDaMos — Buenos Aires, Argentina
  • Fundación Cenit Para La Investigación En Neurociencias — CABA, Argentina
  • CEN Centro Especializado en Neurociencias — Córdoba, Argentina
  • Sanatorio Morra S.A. — Córdoba, Argentina
  • Instituto Kremer — Córdoba, Argentina
  • Centro Médico Luquez — Córdoba, Argentina
  • INSA Instituto de Neurociencia San Agustin — La Plata, Argentina
  • Global Psy Asociación Civil — La Plata, Argentina
  • Resolution Psychopharmacology Research Institute — Mendoza, Argentina
  • Centro de Investigación y Asistencia en Psiquiatría (CIAP) — Rosario, Argentina
  • Fundacion Estudios Clinicos — Rosario, Argentina
  • Hospital das Clínicas da UFMG — Belo Horizonte, Brazil
  • Chronos Pesquisa Clínica — Brasília, Brazil
  • Instituto de Pesquisa clinica de Campinas — Campinas, Brazil
  • Trial Tech — Curitiba, Brazil
  • Clinilive — Maringá, Brazil
  • Instituto Atena de Pesquisa Clinica — Natal, Brazil
  • Ruschel Medicina e Pesquisa Clínica — Rio de Janeiro, Brazil
  • Instituto Apice — Salvador, Brazil
  • CPQuali Pesquisa Clínica — São Paulo, Brazil
  • Clinica Viver - Centro de Desospitalizacao Humana — São Paulo, Brazil
  • PSEG Centro de Pesquisa Clínica — São Paulo, Brazil
  • The Second Xiangya Hospital of Central South University — Changsha, China
  • The Fourth People's Hospital of Chengdu — Chengdu, China
  • The Seventh People's Hospital of Hangzhou — Hangzhou, China
  • Suzhou Guangji Hospital — Suzhou, China
  • Tianjin Anding Hospital — Tianjin, China
  • Wuhu Hospital of Beijing Anding hospital — Wuhu, China
  • Xi An Mental Health Center — Xi'an, China
  • Zhumadian Psychiatric Hospital — Zhumadian, China
  • Galaxy Superspeciality Hospital — Aurangabad, India
  • All India Institute of Medical Sciences (AIIMS) - Bhopal — Bhopal, India
  • Dharwad Institute Of Mental Health And Neurosciences — Dharwad, India
  • Calida Rehab - Karjat — Karjat, India
  • Shree Mahalaxmi DIATONE Institute — Kolhāpur, India
  • Dr. Ram Manohar Lohia Institute of Medical Sciences — Lucknow, India
  • Career Institute of Medical Sciences and Hospital - Lucknow — Lucknow, India
  • D.Y. Patil Hospital — Navi Mumbai, India
  • Medipoint Hospitals Pvt. Ltd. — Pune, India
  • Lifepoint Multispeciality Hospital — Pune, India
  • Sowmanasya Hospital and Institute of Psychiatry — Tiruchirappalli, India
  • Uematsu Mental Clinic — Chikugo, Japan
  • Horikoshi Mental Somatic Clinic — Fukushima, Japan
  • Seinan Hospital — Hachinohe, Japan
  • Fujimidai Hospital — Hiratsuka, Japan
  • Rainbow and Sea Hospital — Karatsu, Japan
  • National Center of Neurology and Psychiatry — Kodaira, Japan
  • Yuge Hospital — Kumamoto, Japan
  • Hirota Clinic — Kurume, Japan
  • Asuka Hospital — Machida, Japan
  • Arata Clinic — Nagasaki, Japan
  • Yutaka Clinic — Sagamihara, Japan
  • Sho Midori Hospital — Saitama, Japan
  • Himorogi Psychiatric Institute - Tokyo - Ichigayatamachi — Tokyo, Japan
  • Okehazama Hospital — Toyoake, Japan
  • Yamagata Sakuracho Hospital — Yamagata, Japan
  • Shioiri Mental Clinic — Yokosuka, Japan
  • Changhua Christian Hospital — Changhua, Taiwan
  • Keelung Chang Gung Memorial Hospital — Keelung, Taiwan
  • Chung Shan Medical University Hospital — Taichung, Taiwan
  • National Cheng Kung University Hospital — Tainan, Taiwan
  • National Taiwan University Hospital — Taipei, Taiwan
  • Taipei City Hospital - Songde Branch — Taipei, Taiwan
  • Taipei Medical University Hospital — Taipei, Taiwan
  • Taipei Veterans General Hospital — Taipei, Taiwan
  • Tri-Service General Hospital — Taipei, Taiwan
  • Chang Gung Medical Foundation-Linkou Branch — Taoyuan, Taiwan
Sponsored

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record