RECRUITING Not applicable ClinicalTrials.gov

Speech Learning and Speech Production in Parkinson's Disease

Sponsor: State University of New York at Buffalo • ClinicalTrials.gov ID: NCT07403539

Registry updated: 2026-09-22

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Description

Parkinson's disease, a common movement disorder that results from a breakdown in the brain, often leads to challenges with talking, but less is known about the relationship between difficulties with talking and difficulties with learning to understand speech. By linking these two abilities in individuals with Parkinson's disease using a precision medicine approach, this project seeks to build a basis for new therapies that help people with Parkinson's disease both understand better and speak more clearly.

Interventions

Intensity learning (Behavioral)
Participants will be asked to pair sentences that vary in their sound intensity to one of three colored squares (red, yellow, or blue)
Intensity discrimination (Behavioral)
Participants will hear two sentences that are either the same or different in their sound intensity and will be asked to indicate whether the sentences were of the same or different intensities
Rate learning (Behavioral)
Participants will be asked to pair sentences that vary in their spoken rate to one of three colored squares (red, yellow, or blue)
Rate discrimination (Behavioral)
Participants will hear two sentences that are either the same or different in their spoken rate and will be asked to indicate whether the sentences were of the same or different rates

Eligibility criteria

Inclusion Criteria: * Diagnosis of Parkinson's disease * Native speaker of North American English * Use a drug that includes levodopa * Resident of the United States Exclusion Criteria: * Any history of language, hearing or speech disorder outside of Parkinson's disease * Other gross neurological impairment such as Alzheimer's disease or stroke * Significant hearing loss and/or use of a hearing aid or cochlear implant

Conditions

Parkinson's Disease

Locations

State University of New York at Buffalo — Buffalo, New York, United States

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record

Accelerate Your Clinical Trial Recruitment