RECRUITING Phase 4 ClinicalTrials.gov

Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSD

Sponsor: Dr. Dean Reeves Clinic • ClinicalTrials.gov ID: NCT07382596

Registry updated: 2026-09-16

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Description

PTSD is a chronic mental health condition that drastically reduces an individual's quality of life Dextrose injection with a small needle has been used for chronic pain patients and observational results have shown it to be effective in reducing anxiety, brain fog, and depression in patients with PTSD. This randomized trial will compare dextrose injection with an injection control of normal saline (NS)

Interventions

Dextrose 5% in water bilateral injection (Drug)
Injection under the investing fascia of the sternocleidomastoid muscle
Normal saline bilateral injection (Drug)
Injection under the investing fascia of the sternocleidomastoid muscle

Eligibility criteria

Inclusion Criteria: * Inclusion Criteria: * Not involved in another study of PTSD treatment * Reliable transportation * Comfortable with computers * Tried 2 or more medications for treatment of PTSD symptoms * Tried 2 or more non-medication treatments for PTSD symptom * No known life-threatening illness * Not taking daily narcotics * Not having 3 or more alcoholic drinks on an average day * No active suicidal plans * No major surgery plans * No major life stress that might interfere with completing study * Symptoms for more than 1 year * Not planning to move for next 18 months. * Living within an hour of Portland, OR, Madison, WI, or Lexington, KY * Wiling to provide 2 email and 2 phone contact methods * Willing to answer questions on multiple occasions over the course of a year. * Willing to be assigned to 3 months of usual care treatment * No diagnosis of schizophrenia, Borderline Personality Disorder, or Bipolar Disorder. * No severe needle phobia * Chronic pain ≤ 5/10 * PCL-C score ≥ 50 Exclusion Criteria: \-

Conditions

PTSD

Locations

Wellward Medical — Lexington, Kentucky, United States
NW Regen — Portland, Oregon, United States
Paul Johnson, MD. — Portland, Oregon, United States
Medical Procedures of Wisconsin — Madison, Wisconsin, United States

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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