N
← Back to Search
Sponsored

Accelerate Your Clinical Trial Recruitment

Reach thousands of high-intent patients matching your specific inclusion criteria.

Start Campaign
RECRUITING Not applicable ClinicalTrials.gov

Digital Health Intervention to Improve TPT Uptake

Sponsor: Arba Minch University • ClinicalTrials.gov ID: NCT07313995

Registry updated: 2026-09-25
Ad

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Check Eligibility →

Description

Despite the evidence of the prevention and control measures of tuberculosis (TB), it still has an impact on the health, social, and economic aspects of the population. Specifically, tuberculosis in children and newly diagnosed TB cases show there is current transmission of TB; to reduce this transmission and to attain the end TB strategy, preventing household TB transmission plays a great role. However, initiation and completion of TB preventive therapy (TPT) among close contacts of index TB patients are suboptimal. Some of the identified factors of low TPT initiation and completion are insufficient patient education, inadequate understanding of TPT, health professionals' perception, parental knowledge, and belief. The digital health intervention is currently being studied as a suggested health intervention that improves the utilization of health care services, including treatment adherence. A systematic review shows that TB treatment outcomes improved with the use of patient education, counseling, text reminders, and digital health technologies. However, other literature indicates controversial results, including our systematic review result, which identified that video directly observed therapy and text message (digital intervention) have no significant effect on TPT completion. In addition, the studies are scarce; therefore, this study aims to assess the effect of video-based education intervention combined with text message reminder (digital health intervention) in improving the initiation and completion of TPT among close contacts of drug-sensitive pulmonary TB patients in South Ethiopia. The study hypothesizes that digital health intervention for close contacts of index drug-sensitive pulmonary TB patients will lead to higher TPT initiation and completion rates than standard care.

Interventions

  • Digital health intervention (Behavioral)
    The treatment arm will provide a digital health intervention (video-based health education) in addition to standard care. Video-based education will be provided for 5-7 minutes every week for three weeks.

Eligibility criteria

Inclusion Criteria: * All household and close contacts of drug-sensitive pulmonary TB patients * Living in the catchment area of the selected health facility * Willing to stay for at least 4 months in the catchment area Exclusion Criteria: * Individuals with a known allergy to TPT drugs or those contraindicated for TPT drugs * Close contacts screened as symptomatic for TB * Close contacts with drug-resistant TB * Temporary residents staying for less than 4 months

Conditions

Tuberculosis, Pulmonary

Locations

  • Arba Minch General Hospital and Dilfana Primary Hospital — Arba Minch, South Ethiopia, Ethiopia
  • Chano Health center — Arba Minch, South Ethiopia, Ethiopia
  • Gerese Primary Hospital — Arba Minch, South Ethiopia, Ethiopia
  • Shelle Health center — Arba Minch, South Ethiopia, Ethiopia
  • Birbir Primary Hospital — Birbir, South Ethiopia, Ethiopia
  • Chencha Generl Hospital — Chencha, South Ethiopia, Ethiopia
  • Zadha Health center — Chencha, South Ethiopia, Ethiopia
  • Bulki Health center — Felege Neway, South Ethiopia, Ethiopia
  • Dombe Health center — Felege Neway, South Ethiopia, Ethiopia
  • Galma Health center — Felege Neway, South Ethiopia, Ethiopia
  • Lotte Health center — Felege Neway, South Ethiopia, Ethiopia
  • Shefite Health center — Felege Neway, South Ethiopia, Ethiopia
  • Sawla General Hospital and Sawla Health Center — Felege Neway, South Ethiopia, Ethiopia
  • Laha Primary Hospital — Laha, South Ethiopia, Ethiopia
Sponsored

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record