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The Use of Cannabidiol Suppositories for Sexual Pain

Sponsor: London Metropolitan University • ClinicalTrials.gov ID: NCT07271030

Registry updated: 2026-08-25

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Description

Research aim: To determine how cannabidiol suppositories might reduce sexual pain during intimacy. Outcomes are also hoped to increase sexual functioning, well-being, and quality of life. Research intention: If cannabidiol suppository intervention reduces sexual pain and increases general well-being, then this research would be repeated on a larger scale, targeting psychosexual services. A brief overview of the intervention: Quantitatively, randomisation of cannabidiol suppositories will be into dose-specific groups. The intervention will be delivered over a period of one month, with follow-up scheduled at 12 weeks. Qualitatively, participants were asked approximately eight open-ended feedback questions throughout the study.

Interventions

Cannabidiol suppository intervention 1 (Dietary supplement)
Cannabidiol suppository dose specific 30mg
Cannabidiol suppository intervention 2 (Dietary supplement)
Cannabidiol suppository dose specific 50mg
Cannabidiol suppository intervention 3 (Dietary supplement)
Cannabidiol suppository dose specific 100mg
Non cannabidiol group control (Other)
Care as usual group

Eligibility criteria

Inclusion Criteria: * Has previously used cannabidiol in any capacity and has not experienced any allergic reaction * Is experiencing sexual pain * There will be an absence of co occurring difficulties * Has attempted sexual intercourse in the last month * Age 18 years or older * Read and write English * Patient Health Questionnaire 9 screening score range between 0-9 mild * General Anxiety Disorder 7 screening score range between 0-9 mild * There are no restrictions on sex, gender, sexuality, or disability Exclusion Criteria: Has experienced an allergic reaction to cannabidiol in any capacity * Has not attempted sexual intercourse in the last month * Has co occurring difficulties * Aged below 18 years old * Are not experiencing sexual pain * Patient Health Questionnaire 9 screening score range between moderate to severe - 10-27 * General Anxiety Disorder 7 screening score range between 10- 21.

Conditions

Well-Being, Psychological Quality of Life Sexual Behavior Sexual Pain Disorder

Locations

School of Social Sciences and Professions — London, United Kingdom

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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