N
← Back to Search
Sponsored

Accelerate Your Clinical Trial Recruitment

Reach thousands of high-intent patients matching your specific inclusion criteria.

Start Campaign
RECRUITING Phase 3 ClinicalTrials.gov

Building Adaptive School-based Interventions for Caries

Sponsor: University of Pennsylvania • ClinicalTrials.gov ID: NCT07265830

Registry updated: 2026-09-10
Ad

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Check Eligibility →

Description

Dental caries (tooth decay) is the world's most prevalent noncommunicable disease. Current preventive and therapeutic treatments are available that can be provided in a school-based health service environment. However, not all children respond to care, and school programs can result in under- or over-treatment, leaving children at high risk. The Building Adaptive School-based Interventions for Caries (BASICS) study will identify the optimal sequence and intensity of these treatments to minimize nonresponse, creating adaptive interventions tailored to specific needs in order to personalize school-based dental medicine.

Interventions

  • Silver Diamine Fluoride (38%) (Device)
    Topically applied silver diamine fluoride 38% solution
  • Glass Ionomer Sealant (Device)
    GIC Dental Sealants
  • Fluoride Varnishes (Device)
    Topically applied fluoride varnish (FV)
  • Hygiene Intervention (Behavioral)
    Behavioral intervention to improve dental hygiene

Eligibility criteria

Inclusion Criteria: 1. Be enrolled in participating schools 2. Be between the ages of 5 and 13 years 3. Provide parental/guardian informed consent 4. Child assent Exclusion Criteria: 1. Ulcerative gingivitis or stomatitis 2. Known sensitivity to silver or other heavy-metal ions 3. More than six affected sites 4. Those who have had full mouth gingivectomies 5. Patients showing abnormal skin sensitization in daily circumstances 6. Those who have had pulp capping

Conditions

Dental Caries

Locations

  • Smiles For Students — Glenwood Springs, Colorado, United States
Sponsored

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record