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RECRUITING Not applicable ClinicalTrials.gov

Using Strength Tests to Better Understand How Pancreatic Cancer Affects Muscle Mass and Quality of Life

Sponsor: British Columbia Cancer Agency • ClinicalTrials.gov ID: NCT07255001

Registry updated: 2026-09-15
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Description

The goal of this clinical trial is to measure hand grip strength in adults with pancreatic ductal adenocarcinoma (PDAC). The main questions it aims to answer are: * Is it feasible to measure hand grip strength as part of a clinic visit? * Are changes in hand grip strength related to changes in body composition? * Is hand grip strength related to a person's well-being? * Is hand grip strength related to how a tumour responds to treatment? Participants will squeeze a device with their hand to measure their hand grip strength and complete questionnaires about their well-being when they are seen in clinic for their regular medical care for PDAC.

Interventions

  • Hand grip strength assessments using a dynamometer (Device)
    Squeeze a dynamometer with one hand to measure hand grip strength.

Eligibility criteria

Inclusion Criteria: * Age 18 years or older. * Histological and/or radiological diagnosis of resectable, non-resectable, or metastatic PDAC. For resectable PDAC, adjuvant setting only. * ECOG performance status 0-2. * Life expectancy greater than 6 months as judged by the investigator. * Planned for treatment, either as part of routine care or in combination with an investigational agent within another study. * Ability to hold a dynamometer with one hand. Exclusion Criteria: * Individuals with CT imaging performed outside of Vancouver, BC, Canada. * Individuals who are unfit to undergo CT imaging of the third lumbar vertebra (L3). * Individuals who are currently participating in a structured moderate intensity resistance training program. * Individuals who are otherwise judged by the investigator to be unfit to proceed with this protocol. * Unable to comply with study assessments and follow-up.

Conditions

Pancreatic Ductal Adenocarcinoma (PDAC) Hand Grip Strength

Locations

  • BC Cancer — Vancouver, British Columbia, Canada
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record