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RECRUITING Phase 4 ClinicalTrials.gov

A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)

Sponsor: Eli Lilly and Company • ClinicalTrials.gov ID: NCT07247084

Registry updated: 2026-09-09
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Description

The purpose of this study is to evaluate tirzepatide within a real-world setting to assess body weight loss and incidence of type 2 diabetes in adults without diabetes who have obesity and at least one weight-related comorbid condition. Eligible participants must be registered patients at a participating site. Participation in the study will last about 260 weeks.

Interventions

  • Tirzepatide (Drug)
    Administered SC
  • Standard of Care (Other)
    Standard of care

Eligibility criteria

Inclusion Criteria: * Have a body mass index ≥30 and ≤34.9 kilogram per square meter (kg/m2) * Have an increased waist to height ratio (defined by \>0.5) * Have at least one weight related comorbid condition * Have had at least one attempt to lose weight with lifestyle intervention (diet and physical activity) Exclusion Criteria: * Have type 1 diabetes, type 2 diabetes, or any other types of diabetes * Have had a change in body weight of greater than 5 kilograms (11 pounds) within 90 days prior to screening

Conditions

Obesity

Locations

  • P91604 St John's Medical Centre — Altrincham, United Kingdom
  • P89008 Ashton Medical Group — Ashton-under-Lyne, United Kingdom
  • Y02319 SSP Bolton General Practice — Bolton, United Kingdom
  • P83012 Tower Family Healthcare — Bury, United Kingdom
  • P91014 Washway Road Medical Centre — Cheshire, United Kingdom
  • P88007 Cheadle Hulme Medical Group (was Cheadle Hulme Health Centre) (Bridge House) — Cheshire, United Kingdom
  • Y02790 SSP Bolton Medical Centre — Great Lever, United Kingdom
  • P89002 The Brooke Surgery — Hyde SK14, United Kingdom
  • P84035 Bodey Medical Centre — Manchester, United Kingdom
  • P84630 The Arch Medical Practice — Manchester, United Kingdom
  • P84678 Didsbury Medical Centre — Manchester, United Kingdom
  • P84017 Ladybarn Group Practice — Manchester, United Kingdom
  • P84068 Chorlton Family Practice — Manchester, United Kingdom
  • P84012 Northenden Group Practice — Manchester, United Kingdom
  • P86004 Peterloo Medical Centre — Manchester, United Kingdom
  • P83025 St Gabriels Medical Centre — Manchester, United Kingdom
  • P87019 Silverdale Medical Practice — Manchester, United Kingdom
  • P91006 Urmston Group Practice — Manchester, United Kingdom
  • P92620 SSP Ince Surgery (Lower Ince) — Manchester, United Kingdom
  • P84034 Barlow Medical Centre — Manchester, United Kingdom
  • P85010 Woodlands Medical Practice — Oldham, United Kingdom
  • P85011 CH Medical Practice — Oldham, United Kingdom
  • P86022 Stonefield Street Surgery — Rochdale, United Kingdom
  • P91021 Firsway Health Centre — Sale, United Kingdom
  • P91013 Boundary House Medical Centre — Sale, United Kingdom
  • P87027 Langworthy Medical Practice — Salford, United Kingdom
  • P88632 Stockport Medical Group — Stockport, United Kingdom
  • P87016 The Sides Medical Centre — Swinton, United Kingdom
  • P87025 The Lakes Medical Practice — Swinton, United Kingdom
  • Y02322 SSP Leigh Family Practice — Wigen, United Kingdom
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record