RECRUITING Not applicable ClinicalTrials.gov

Moving Forward With Myeloma: A Lifestyle Intervention for Individuals With Multiple Myeloma

Sponsor: Medical College of Wisconsin • ClinicalTrials.gov ID: NCT07236502

Registry updated: 2026-10-06

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Description

The purpose of this project is to evaluate the impact of a 16-week lifestyle program that promotes changes in eating and exercise patterns. The main questions the study will answer are: Do improvements in eating and exercise patterns lead to improved physical function, quality of life and blood biomarkers of biologial aging among individuals with multiple myeloma? Participants will complete study activities 3-4 times during the study. 1. In-person assessment to measure physical function, height/weight, body composition, and includes a blood draw 2. Surveys completed online or on paper at home

Interventions

Immediate intervention (Behavioral)
16-session intervention that facilitates changes in nutrition and physical activity behaviors to promote improvements in physical function, Patient Reported Outcomes, body composition and general health
Waitlist (Other)
Participants will be asked to maintain their behavior over the 16 week waitlist period and will receive weekly text message relating positive messages unrelated to lifestyle

Eligibility criteria

Inclusion Criteria: 1. Adult (≥ 18 years) 2. Diagnosed with MM at least one year prior to study enrollment 3. 100 days post transplant (if applicable) 4. Has access to a smart phone or device with internet access 5. Be deemed "clinically stable" by their physician guided by the following: 1. not expected to receive therapies beyond maintenance (for 100 days) 2. no new significant myeloma symptoms (e.g., fractures, spinal stability concerns) meriting changes in anti-neoplastic therapies in the next 30 days; AND 3. stable performance status (ECOG 0-2) assessed in the last 3 months 6. No reports of severe pain \> Grade 3 \[defined by the NCI CTCAE as tumor, neurologic, bone, or other pain interfering with self-care ADLs (bathing, dressing, toileting, continence, feeding)\]. 7. Able to participate in PA and strength training per clinician approval and confirmed by participant 8. Able to understand and willing to sign a written informed consent document 9. English proficient for reading and writing Exclusion Criteria: 1. Coexistent amyloidosis, POEMS syndrome will not be approached 2. Fully adherent to the ACS nutrition and physical activity guidelines 3. If participant is of child-bearing age they cannot be pregnant, planning to come pregnant or lactating during the study period 4. On another interventional clinical trial that precludes co-enrollment 5. Psychiatric or other clinical conditions that preclude study compliance 6. Other important medical or safety considerations at the discretion of the investigator(s) and/or approving clinician

Conditions

Multiple Myeloma (MM)

Locations

Loyola University Chicago — Maywood, Illinois, United States
Medical College of Wisconsin — Milwaukee, Wisconsin, United States

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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