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RECRUITING Not applicable ClinicalTrials.gov

Handgrip Training and Brain Blood Flow Regulation

Sponsor: Florida State University • ClinicalTrials.gov ID: NCT07223645

Registry updated: 2026-10-07
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Description

This study aims to investigate the effect of isometric handgrip training on brain blood vessel function in physically inactive adults. Isometric handgrip training is a promising strategy for lowering blood pressure and improving vascular health, but no previous investigations have studied the effect of training on markers of brain blood vessel function. Based on previous work showing improvements in vascular function after isometric handgrip training, we hypothesize that isometric handgrip training will improve key markers of cerebrovascular function.

Interventions

  • Handgrip Training (Device)
    Handgrip training 3 days per week for 8 weeks

Eligibility criteria

Inclusion Criteria: * 18 to 35 years old * Body mass index ≤30 kg/m2 (without obesity) * Physically inactive (not meeting the current recommendations of ≥150 minutes per week of moderate-to-vigorous aerobic exercise and not ≥2 days per week of resistance training) in last 6 months * Have a smartphone and are willing to download mobile applications used in this project Exclusion Criteria: * Having an overt chronic condition (e.g., cardiovascular, cerebrovascular, etc.) * Being pregnant, planning to become pregnant, or breastfeeding/lactating * Regular use of nicotine products in the past 6 months * Recent head injury/trauma or concussion

Conditions

Inactivity/Low Levels of Exercise

Locations

  • Florida State University — Tallahassee, Florida, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record