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RECRUITING Not applicable ClinicalTrials.gov

A Tailored Medication Adherence-Promotion Intervention for Adolescents and Young Adults With Cancer

Sponsor: Children's Hospital Medical Center, Cincinnati • ClinicalTrials.gov ID: NCT07223463

Registry updated: 2026-09-24
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Description

The goal of this clinical trial is to learn if a tailored intervention can help make it easier for adolescents and young adults with cancer to take their medications. The main questions the researchers are trying to answer are: * Does the tailored intervention increase adherence? * Does the tailored intervention improve quality of life? * Does the tailored intervention reduce health care utilization? The researchers will compare the tailored intervention to a uniform standard of care intervention (an intervention designed to be similar to what is currently happening in clinical care) to see if the tailored intervention works to improve adherence. Participants will: * Use an electronic pill bottle or box to store their medication * Participate in intervention sessions * Complete surveys before the intervention, after the intervention, and 6-months later

Interventions

  • Tailored Program (Behavioral)
    Participants will participate in 4 sessions with a coach, 1 every other week. During these sessions, the participant will work with their coach to identify a barrier to adherence they would like to target. Then, they will work with their coach to create an action plan using evidence-based behavior change techniques to address this barrier. In between sessions (on alternating weeks), the coach will check-in with a text reminder about the plan.
  • Feedback Program (Uniform Standard of Care) (Behavioral)
    Participants will receive weekly text messages with feedback about their adherence and guidance for requesting additional support if desired

Eligibility criteria

Inclusion Criteria: * Patient is 15.00 to 24.99 years of age * Patient is diagnosed with cancer * Patient is prescribed an oral anticancer/antitumor agent or prophylaxis Exclusion Criteria: * Patient is not fluent in English * Patient evidences significant cognitive deficits * Patient's medical status or treatment precludes participation * Patient enrolled on a medical trial requiring medication storage in a trial-provided container * Patient demonstrates greater than or equal to 95% adherence during run-in period * Patient declines to use or has difficulty using electronic adherence monitoring device during run-in

Conditions

Cancer Medication Adherence

Locations

  • The University of Kansas Medical Center — Kansas City, Kansas, United States
  • Columbia University Irving Medical Center — New York, New York, United States
  • Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States
  • Seattle Children's Hospital — Seattle, Washington, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record