RECRUITING Phase 3 ClinicalTrials.gov

A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)

Sponsor: Boehringer Ingelheim • ClinicalTrials.gov ID: NCT07220083

Registry updated: 2026-10-14

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Description

PODOMOUNT-pFSGS This study is open to adults and adolescents with a kidney condition called focal segmental glomerulosclerosis (FSGS). The purpose of this study is to find out whether a medicine called BI 764198 helps people with FSGS. Participants are put into 2 groups randomly, which means by chance. Every participant has an equal chance of being in each group. One group takes BI 764198 tablets, and the other group takes placebo tablets. Placebo tablets look like BI 764198 tablets but do not contain any medicine. Participants take a tablet once a day for up to 2 years. All participants also continue their standard medication for FSGS. Participants are in the study for up to 2 years. During this time, they visit the study site about every 3 months. Participants regularly collect urine samples. This is done to check their kidneys. The results are compared between the two groups to see whether the treatment works. The doctors also regularly check participants' health and take note of any unwanted effects.

Interventions

BI 764198 (Drug)
BI 764198
Placebo (Drug)
Placebo matching BI 764198

Eligibility criteria

Inclusion criteria: 1. Male or female participants ≥12 years old on the day of signing informed consent/assent (Visit 1) 2. Weight of ≥40 kg at the screening visit (Visit 1) 3. Body mass index (BMI) of ≤40 kg/m² at the screening visit (Visit 1) 4. Participants with a diagnosis prior to the screening visit (Visit 1) of either: * Biopsy-confirmed primary focal segmental glomerulosclerosis (pFSGS) (based on Investigator's judgement) OR * Genetic focal segmental glomerulosclerosis (FSGS) resulting from a gain-of-function mutation in the transient receptor potential cation subfamily C member 6 (TRPC6) gene (based on historical genetic test) 5. Urine protein-creatinine ratio (UPCR) ≥1500 mg/g based on the mean of the spot urine sample and first morning void (FMV) urine sample (both assessed by central laboratory) at the screening visit (Visit 1) 6. Estimated glomerular filtration rate (eGFR) * For adult participants (≥18 years): ≥25 mL/min/1.73 m² (chronic kidney disease epidemiology collaboration (CKD-EPI) formula based on serum cystatin C) at the screening visit (Visit 1) * For adolescent participants (12 to \<18 years): ≥25 mL/min/1.73 m² based on chronic kidney disease under 25 years (CKiD U25) formula using serum cystatin C at the screening visit (Visit 1) Further inclusion criteria apply. Exclusion criteria: 1. Known monogenic or syndromic causes of FSGS (with the exception of TRPC6 gain-of-function gene mutations) 2. Clinical or histologic evidence of secondary adaptive or toxic forms of FSGS (based on Investigator's judgement) 3. FSGS of undetermined cause (FSGS-UC) with a diagnosis prior to the screening visit (Visit 1) (based on Investigator's judgement) 4. A history of organ transplantation or planned organ transplantation during the course of the trial 5. Use of intravenous immunosuppressive agents (e.g. cyclophosphamide, rituximab, obinutuzumab) in the last 6 months prior to screening (Visit 1) Further exclusion criteria apply.

Conditions

Focal Segmental Glomerulosclerosis

Locations

Alabama Kidney Research — Alabaster, Alabama, United States
Apogee Clinical Research — Huntsville, Alabama, United States
Southwest Kidney Institute — Surprise, Arizona, United States
West Coast Kidney Institute — Fremont, California, United States
Kidney Disease Medical Group — Glendale, California, United States
Amicis Research Center - Balboa — Granada Hills, California, United States
Valiance Clinical Research — Huntington Park, California, United States
Academic Medical Research Institute - Glendale — Los Angeles, California, United States
Kaiser Permanente - Los Angeles Medical Center — Los Angeles, California, United States
University of California Los Angeles — Los Angeles, California, United States
Valley Renal Medical Group - Northridge — Northridge, California, United States
Shasta Critical Care Specialists — Redding, California, United States
North America Research Institute — San Dimas, California, United States
Kaiser Permanente - French Campus — San Francisco, California, United States
Valiance Clinical Research-Tarzana-68237 — Tarzana, California, United States
National Institute of Clinical Research - Victorville — Victorville, California, United States
Kidney Associates of Colorado - Denver — Denver, Colorado, United States
Colorado Kidney Care — Denver, Colorado, United States
George Washington University Medical Faculty Associates — Washington D.C., District of Columbia, United States
Florida Kidney Physicians - Boca Raton — Boca Raton, Florida, United States
Florida Kidney Physicians, LLC - Fort Lauderdale — Fort Lauderdale, Florida, United States
Total Research Group, LLC — Miami, Florida, United States
CTR Oakwater, LLC — Orlando, Florida, United States
Coastal Nephrology and Associates — Port Charlotte, Florida, United States
Florida Kidney Physicians - Riverview/Brandon — Riverview, Florida, United States
Emory Children's Center — Atlanta, Georgia, United States
Coastal Medical Research, LLC — Brunswick, Georgia, United States
Southeast Kidney Associates - East Point — East Point, Georgia, United States
Memorial Health University Hospital — Savannah, Georgia, United States
Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois, United States
Northwestern University — Chicago, Illinois, United States
Endeavor Health — Evanston, Illinois, United States
Kidney Care Center - Olympia Fields — Olympia Fields, Illinois, United States
Nephrology Physicians - Mishawaka — Mishawaka, Indiana, United States
EmVenio Research Inc. - Kansas City — Kansas City, Kansas, United States
Wichita Nephrology Group — Wichita, Kansas, United States
Renal Associates of Baton Rouge — Baton Rouge, Louisiana, United States
Northwest Louisiana Nephrology — Shreveport, Louisiana, United States
Johns Hopkins Hospital — Baltimore, Maryland, United States
Joslin Diabetes Center — Boston, Massachusetts, United States
Henry Ford Hospital — Detroit, Michigan, United States
Paragon Health Nephrology Center - Kalamazoo — Kalamazoo, Michigan, United States
St. Clair Nephrology Research, LLC - Shelby Township — Utica, Michigan, United States
Nephrology Associates - Columbus — Columbus, Mississippi, United States
Nephrology & Hypertension Associates, Ltd. — Tupelo, Mississippi, United States
Elixia MNA, LLC — City of Saint Peters, Missouri, United States
DaVita Clinical Research-Las Vegas-67781 — Las Vegas, Nevada, United States
New York Nephrology and Dialysis Access Surgery, PC — Clifton Park, New York, United States
NYU Langone Nephrology Associates-Mineola — Mineola, New York, United States
Duke University Medical Center — Durham, North Carolina, United States
Carolina Kidney Associates — Greensboro, North Carolina, United States
Cardinal Clinical Research, LLC - Shelby — Shelby, North Carolina, United States
Americare Kidney Institute - Brunswick — Brunswick, Ohio, United States
The Kidney and Hypertension Center — Cincinnati, Ohio, United States
Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States
Nationwide Children's Hospital — Columbus, Ohio, United States
The Ohio State University Wexner Medical Center — Columbus, Ohio, United States
Northeast Clinical Research Center — Bethlehem, Pennsylvania, United States
Clinical Renal Associates — Exton, Pennsylvania, United States
University of Pennsylvania — Philadelphia, Pennsylvania, United States
Nephrology Associates, Inc — East Providence, Rhode Island, United States
Palmetto Nephrology — Orangeburg, South Carolina, United States
Southeast Renal Research Institute — Chattanooga, Tennessee, United States
Texas Tech University Health Sciences Center-Amarillo-63885 — Amarillo, Texas, United States
The Healing Kidneys Institute — Conroe, Texas, United States
Advanced Dallas Hospital and Clinics — Dallas, Texas, United States
Nephrotex Research Group — Dallas, Texas, United States
University of Texas Medical Branch at Galveston — Galveston, Texas, United States
Sanmora Bespoke Clinical Research Solutions — Grand Prairie, Texas, United States
Provecta Researh Network — Houston, Texas, United States
Provecta Research Path Forward Ventures — Humble, Texas, United States
Primary Children's Hospital — Salt Lake City, Utah, United States
Utah Kidney Research Institute — Salt Lake City, Utah, United States
Virginia Nephrology — Arlington, Virginia, United States
Nephrology Associates of Northern Virginia — Fairfax, Virginia, United States
Virginia Commonwealth University — Richmond, Virginia, United States
West Virginia University Medicine — Morgantown, West Virginia, United States
Terapia Renal Domiciliaria — Buenos Aires, Argentina
Hospital Italiano de Buenos Aires — CABA, Argentina
CEMIC — CABA, Argentina
Centro Medico Dra Laura Maffei — Ciudad Autonoma Buenos Aires, Argentina
Clinica Privada Velez Sarfield — Córdoba, Argentina
Hospital Universitario Austral — Pilar, Argentina
CardioAlem Investigaciones — San Isidro, Argentina
Centro Integral de Medicina Respiratoria - CIMER — San Miguel de Tucumán, Argentina
Grupo MIT - Medicina Interdisciplinaria y Trasplantes — Santa Fe, Argentina
Concord Repatriation General Hospital — Concord, New South Wales, Australia
Nepean Hospital — Kingswood, New South Wales, Australia
St George Hospital — Kogarah, New South Wales, Australia
The Children's Hospital at Westmead — Westmead, New South Wales, Australia
Royal Brisbane and Women's Hospital — Herston, Queensland, Australia
Griffith Health — Southport, Queensland, Australia
Royal Adelaide Hospital — Adelaide, South Australia, Australia
Sunshine Hospital — AT Albans, Victoria, Australia
Royal Melbourne Hospital — Parkville, Victoria, Australia
AZORG Ziekenhuis — Aalst, Belgium
UZ Leuven — Leuven, Belgium
Centre Hospitalier Universitaire de Liège — Liège, Belgium
Synvia — Campinas, Brazil
Universidade Federal do Ceara — Fortaleza, Brazil
Hospital de Clinicas de Porto Alegre — Porto Alegre, Brazil
Hospital das Clinicas da Universidade Federal de Pernambuco — Recife, Brazil
Fundacao Oswaldo Ramos (Hospital do Rim) — São Paulo, Brazil
Centro de Pesquisa Clínica de Nefrologia do ICHC — São Paulo, Brazil
Instituto da Crianca e do Adolescente — São Paulo, Brazil
Medicinski Centar Hipokrat-N EOOD — Plovdiv, Bulgaria
Medical Center "Pulmovision" — Sofia, Bulgaria
BC Children's Hospital — Vancouver, British Columbia, Canada
Victoria Hospital (LHSC) — London, Ontario, Canada
Toronto General Hospital — Toronto, Ontario, Canada
Maisonneuve-Rosemont Hospital — Montreal, Quebec, Canada
Montreal General Hospital - McGill University Health Centre — Montreal, Quebec, Canada
The First Affiliated Hospital of Baotou Medical College — Baotou, China
Peking University First Hospital — Beijing, China
Beijing Tsinghua Changgung Hospital — Beijing, China
The Second Hospital of Jilin University — Changchun, China
The Second Xiangya Hospital Of Central South University — Changsha, China
West China Hospital, Sichuan University — Chengdu, China
Sichuan Provincial People's Hospital — Chengdu, China
Guangdong Provincial People's Hospital — Guangzhou, China
The First Affiliated Hospital, Zhejiang University — Hangzhou, China
Lanzhou University Second Hospital — Lanzhou, China
The First Affiliated Hospital of Nanchang University — Nanchang, China
Zhongda Hospital Southeast University — Nanjing, China
The First People's Hospital of Nanning — Nanning, China
The First Affiliated Hospital of Guangxi Medical University — Nanning, China
The First Affiliated Hospital of Ningbo University — Ningbo, China
Ruijin Hospital Shanghai Jiao Tong University School of Medicine — Shanghai, China
Huashan Hospital, Fudan University — Shanghai, China
Shanghai General Hospital — Shanghai, China
Shanxi Provincial People's Hospital — Taiyuan, China
Renmin Hospital of Wuhan University — Wuhan, China
First Affiliated Hospital of Xi'an JiaoTong University — Xi'an, China
Zhongshan Hospital Affiliated to Xiamen University — Xiamen, China
University Hospital Dubrava — Zagreb, Croatia
Clinical Hospital Sveti Duh — Zagreb, Croatia
Poliklinika Bonifarm Zagreb — Zagreb, Croatia
Solmed Polyclinic — Zagreb, Croatia
Copenhagen University Hospital, Rigshospitalet — København Ø, Denmark
Zealand University Hospita; Roskilde — Roskilde, Denmark
North Estonia Medical Centre Foundation, Tallinn — Tallinn, Estonia
New Children's Hospital — Helsinki, Finland
Helsinki University Central Hospital, Meilahti hospital — Helsinki, Finland
CHU Amiens-Picardie — Amiens, France
HOP Pellegrin — Bordeaux, France
HOP de la Cavale Blanche — Brest, France
Hopital Henri Mondor — Créteil, France
Hôpital Edouard Herriot — Lyon, France
Hopital Pasteur — Nice, France
CHU de Nîmes — Nîmes, France
Hopital Necker — Paris, France
HOP Nancy — Vandœuvre-lès-Nancy, France
LTD Israeli-Georgian Medical Research Clinic Healthycore — Tbilisi, Georgia
LEPL The First University Clinic of Tbilisi State Medical University — Tbilisi, Georgia
M.Iashvili Children's Hospital — Tbilisi, Georgia
Vivantes Klinikum im Friedrichshain — Berlin, Germany
Universitätsklinikum Köln (AöR) — Cologne, Germany
Universitätsklinikum Hamburg, Eppendorf — Hamburg, Germany
Medizinische Hochschule Hannover — Hanover, Germany
Universitätsklinikum Heidelberg — Heidelberg, Germany
Universität Leipzig — Leipzig, Germany
Universitätsmedizin der Johannes Gutenberg-Universität Mainz — Mainz, Germany
Universitätsklinikum Würzburg AÖR — Würzburg, Germany
University General Hospital of Heraklion — Heraklion, Greece
Univ. Gen. Hosp. of Patras — Pátrai, Greece
Hong Kong Children's Hospital — Hong Kong, Hong Kong
Queen Mary Hospital — Hong Kong, Hong Kong
Aartham Multi Super Speciality Hospital — Ahmedabad, India
Zydus Hospital - Ahmedabad — Ahmedabad, India
AIIMS Bhubaneshwar — Bhubaneswar, India
S.P. Medical College & Associated Group of Hospitals — Bikaner, India
Madras Medical College and Rajiv Gandhi Government General Hospital — Chennai, India
Sri Ramchandra Institute — Chennai, India
Shri Mahant Indiresh Hospital — Dehradun, India
Sir Gangaram Hospital — Delhi, India
Osmania Medical College & Hospital — Hyderabad, India
Nizam's Institute of Medical Sciences — Hyderabad, India
Government Medical College — Kozhikode, India
Sanjay Gandhi Post Graduate Institute of Medical Sciences — Lucknow, India
Kasturba Medical College and Hospital — Manipal, India
Nutema Hospital — Meerut, India
KEM Hospital and Seth G S Medical College — Mumbai, India
P.D. Hinduja National Hospital — Mumbai, India
Noble Hospital Pvt Ltd — Pune, India
Galaxy Lifecare Services Pvt. Ltd. — Varanasi, India
Sunrise Hospital — Vijayawada, India
Azienda Universitaria Ospedaliera Consorziale Policlinico Bari — Bari, Italy
Policlinico S. Orsola-Malpighi — Bologna, Italy
Asst Santi Paolo E Carlo — Milan, Italy
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone — Palermo, Italy
Fondazione Salvatore Maugeri — Pavia, Italy
ASST dei Sette Laghi — Varese, Italy
Kasugai Municipal Hospital — Aichi, Kasugai, Japan
Daido Clinic — Aichi, Nagoya, Japan
Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital — Aichi, Nagoya, Japan
Chiba University Hospital — Chiba, Chiba, Japan
National Hospital Organization Chibahigashi National Hospital — Chiba, Chiba, Japan
Japanese Red Cross Fukuoka Hospital — Fukuoka, Fukuoka, Japan
Kurume University Hospital — Fukuoka, Kurume, Japan
Kobe University Hospital — Hyogo, Kobe, Japan
Saiseikai Yokohamashi Nanbu Hospital — Kanagawa, Yokohama, Japan
Yokohama City University Hospital — Kanagawa, Yokohama, Japan
Nara Prefecture General Medical Center — Nara, Nara, Japan
Niigata University Medical and Dental Hospital — Niigata, Niigata, Japan
Kawasaki Medical School Hospital — Okayama, Kurashiki, Japan
Okayama University Hospital — Okayama, Okayama, Japan
Dokkyo Medical University Saitama Medical Center — Saitama, Koshigaya, Japan
Institute of Science Tokyo Hospital — Tokyo, Bunkyo-ku, Japan
Tokyo Medical University Hachioji Medical Center — Tokyo, Hachioji, Japan
The Jikei University Hospital — Tokyo, Minato-ku, Japan
Tokyo Women's Medical University Hospital — Tokyo, Shinjuku-ku, Japan
Hospital Sultan Idris Shah Serdang — Kajang, Malaysia
Queen Elizabeth Hospital — Kota Kinabalu, Malaysia
Hospital Kuala Lumpur — Kuala Lumpur, Malaysia
University Malaya Medical Centre — Lembah Pantai, Malaysia
Hospital Tuanku Ja'afar — Negeri Sembilan, Malaysia
Sunway Medical Centre — Subang Jaya, Malaysia
Centenario Hospital Miguel Hidalgo — Aguascalientes, Mexico
Health Pharma Professional Research S.A. de C.V. — Mexico City, Mexico
Soltmed Smo — Mexico City, Mexico
Instituto Nacional de Cardiologia Ignacio Chavez — Mexico City, Mexico
Instituto Nacional de Cs Médicas y Nutrición S Zubiran — Mexico City, Mexico
Servicios de Oncología Médica Integral, S.A. de C.V. Sucursal Renal — Monterrey, Mexico
Amsterdam UMC Locatie AMC — Amsterdam, Netherlands
Universitair Medisch Centrum Groningen — Groningen, Netherlands
Waikato Hospital — Hamilton, Waikato Region, New Zealand
Optimal Clinical Trials North — Auckland, New Zealand
New Zealand Clinical Research (NZCR) Christchurch — Christchurch, New Zealand
Taranaki Base Hospital — New Plymouth, New Zealand
Akershus Universitetssykehus HF — Lørenskog, Norway
Oslo Universitetssykehus HF, Ulleval sykehus — Oslo, Norway
Helse Stavanger, Stavanger Universitetssykehus — Stavanger, Norway
Universitetssykehuset Nord-Norge, Tromso — Tromsø, Norway
Manila Doctors Hospital — Manila, Philippines
Promed P.Łach R. Glowacki Sp. j. — Krakow, Poland
Centralny Szpital Kliniczny Uniwersytetu Medycznego w Łodzi — Lodz, Poland
Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu — Poznan, Poland
Uniwersytecki Szpital Kliniczny Nr 2 Pum W Szczecinie — Szczecin, Poland
Samodzielny Publiczny Dzieciecy Szpital Kliniczny Im. Jozefa Polikarpa Brudzinskiego W Warszawie — Warsaw, Poland
Wojskowy Instytut Medyczny Panstwowy Instytut Badawczy — Warsaw, Poland
4th Military Clinical Hospital with a Polyclinic — Wroclaw, Poland
ULS de Almada -Seixal, E. P. E. - Hospital Garcia de Orta — Almada, Portugal
ULS de Amadora/ Sintra, E.P.E. - Hospital Professor Doutor Fernando Fonseca — Amadora, Portugal
ULS de Braga, E.P.E — Braga, Portugal
CHUC - Centro Hospitalar e Universitario de Coimbra, EPE — Coimbra, Portugal
ULS de São José — Lisbon, Portugal
ULS de Santa Maria, E.P.E — Lisbon, Portugal
Unidade Local de Saúde Lisboa Occidental, E.P.E — Lisbon, Portugal
ULS de Loures-Odivelas, E.P.E — Loures, Portugal
ULS de Santo Antônio, E.P.E - Centro Hospitalar Universitário de Santo António — Porto, Portugal
Unidade Local de Saúde da Arrábida,E.P.E — Setúbal, Portugal
Institutul Clinic Fundeni — Bucharest, Romania
Spitalul Clinic Judetean de urgenta Cluj — Cluj-Napoca, Romania
Spitalul Clinic Judetean de Urgenta Bihor — Oradea, Romania
County Emergency Hospital Pius Brinzeu Timisoara — Timișoara, Romania
King Fahad Specialist Hospital - Research Center — Dammam, Saudi Arabia
Imam Abdulrahman bin Faisal University — Dammam, Saudi Arabia
National University Hospital — Singapore, Singapore
Singapore General Hospital — Singapore, Singapore
Tan Tock Seng Hospital — Singapore, Singapore
Detska fakultna nemocnica s poliklinikou Banska Bystrica — Banská Bystrica, Slovakia
Faculty hospital with clinics F.D. Roosevelta — Banská Bystrica, Slovakia
University Hospital and Comenius University in Bratislava, Derer´s Hospital — Bratislava, Slovakia
Univerzitna nemocnica L. Pasteura Kosice — Košice, Slovakia
Univerzitna Nemocnica Martin — Martin, Slovakia
Pusan National University Hospital — Busan, South Korea
Samsung Medical Center — Gangnam-gu, South Korea
Inje University Ilsan Paik Hospital — Goyang, South Korea
Severance Hospital — Seoul, South Korea
Kyung Hee University Hospital at Gangdong — Seoul, South Korea
Ajou University Hospital — Suwon, South Korea
Complejo Hospitalario Torrecárdenas — Almería, Spain
Hospital del Mar — Barcelona, Spain
Hospital Universitari Vall d'Hebron — Barcelona, Spain
Hospital Clínic de Barcelona — Barcelona, Spain
Hospital Sant Joan de Déu — Barcelona, Spain
Hospital Universitario Virgen de las Nieves — Granada, Spain
Hospital Universitario 12 de Octubre — Madrid, Spain
Universitetssjukhuset Linköping — Linköping, Sweden
Skånes universitetssjukhus — Lund, Sweden
Karolinska Universitetssjukhuset — Stockholm, Sweden
Danderyds Sjukhus — Stockholm, Sweden
Uppsala University Hospital — Uppsala, Sweden
University Hospital Bern — Bern, Switzerland
University Hospital Zurich — Zurich, Switzerland
Buddhist Tzu Chi General Hospital-Hualien-20741 — Hualien City, Taiwan
Kaohsiung Chang Gung Memorial Hospital — Kaohsiung City, Taiwan
Far Eastern Memorial Hospital — New Taipei City, Taiwan
Taipei Medical University-Shuang Ho Hospital — New Taipei City, Taiwan
China Medical University Hospital — Taichung, Taiwan
Taichung Veterans General Hospital — Taichung, Taiwan
National Cheng Kung University Hospital — Tainan, Taiwan
National Taiwan University Hospital — Taipei, Taiwan
Chang Gung Memorial Hospital, Linkou — Taoyuan City, Taiwan
King Chulalongkorn Memorial Hospital — Bangkok, Thailand
Maharaj Nakom Chiangmai Hospital — Chiang Mai, Thailand
Adana City Hospital — Adana, Turkey (Türkiye)
Ankara Etlik City Hospital — Ankara, Turkey (Türkiye)
Malatya Inonu University Hospital — Battalgazi / Malatya, Turkey (Türkiye)
Bursa Uludag University — Bursa, Turkey (Türkiye)
Istanbul Capa University — Istanbul, Turkey (Türkiye)
Istanbul Universitesi Cerrahpasa Tip Fakultesi — Istanbul, Turkey (Türkiye)
Kocaeli University Faculty of Medicine Hospital — İzmit, Turkey (Türkiye)
Erciyes University — Melikgazi/Kayseri, Turkey (Türkiye)
Afyon Kocatepe University Hospital — Merkez / Afyonkarahisar, Turkey (Türkiye)
Mersin University Medical Faculty — Mersin, Turkey (Türkiye)
Sakarya Üniversitesi Tıp Fakültesi — Sakarya, Turkey (Türkiye)
Clatterbridge Hospital — Bebington, United Kingdom
Bradford Institute for Health Research — Bradford, United Kingdom
Addenbrooke's Hospital — Cambridge, United Kingdom
St Helier Hospital — Carshalton, United Kingdom
Leicester General Hospital — Leicester, United Kingdom
Royal Free Hospital — London, United Kingdom
King's College Hospital — London, United Kingdom
The James Cook University Hospital — Middlesbrough, United Kingdom
Salford Royal Hospital — Salford, United Kingdom

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