FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors
Sponsor: Fate Therapeutics • ClinicalTrials.gov ID: NCT07216105
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This is a Phase 1 study of FT836 administered in participants with advanced solid tumors. The primary objectives of the study are to evaluate the safety and tolerability of FT836 with or without chemotherapy and/or trastuzumab or cetuximab, and to determine the recommended phase 2 dose (RP2D) of FT836 with or without chemotherapy and/or trastuzumab or cetuximab
Interventions
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FT836
(Drug)
FT836 drug product is administered as an intravenous infusion on multiple days schedule at treatment cycle.
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Cetuximab
(Drug)
Cetuximab administration will begin on Day -4 at the recommended initial dose of 400 mg/m2 as a 120-minute IV infusion
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Trastuzumab
(Drug)
Trastuzumab administration will begin on Day -4 at an initial dose of 4 mg/kg as a 90-minute IV infusion.
Eligibility criteria
Conditions
Locations
- UC San Diego Moores Cancer Center — La Jolla, California, United States
- University of Southern California — Los Angeles, California, United States
- University of Minnesota Masonic Cancer Center — Minneapolis, Minnesota, United States
- Thomas Jefferson University, Sidney Kimmel Cancer Center — Philadelphia, Pennsylvania, United States
- M. D. Anderson Cancer Center — Houston, Texas, United States
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Learn MoreOfficial Source
Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
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