RECRUITING Not applicable ClinicalTrials.gov

LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Protocol for Patients Living With Metastatic Lung Cancer

Sponsor: Medical University of South Carolina • ClinicalTrials.gov ID: NCT07177846

Registry updated: 2026-10-07

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Description

In this pilot randomized controlled trial, patients with metastatic non-small cell lung cancer and at least mild distress (N=80) will be randomized to receive LiveWell, an adapted Dialectical Behavioral Therapy (DBT) Skills Training protocol) or Usual Care. The investigators will evaluate feasibility, acceptability, and preliminary efficacy of LiveWell to reduce distress (primary outcome) and improve psychological well-being, symptom burden, and quality of life (secondary outcomes). The investigators will explore emotion regulation as a potential mechanism of change.

Interventions

LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Program (Behavioral)
LiveWell: Adapted DBT Skills Training for Patients with Metastatic Lung Cancer

Eligibility criteria

Inclusion Criteria: * Age ≥ 18 * AJCC Stage IV non-small cell lung cancer * Receiving treatment with non-curative intent or on active surveillance * English proficiency * Able to provide informed consent * National Comprehensive Cancer Network distress screening score ≥ 3/10 plus endorse at least 1 emotional concern. Exclusion Criteria: * Cognitive impairment * Untreated serious mental illness * Expected survival \< 6 months

Conditions

Survivorship

Locations

Medical University of South Carolina — Charleston, South Carolina, United States

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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