N
← Back to Search
Sponsored

Accelerate Your Clinical Trial Recruitment

Reach thousands of high-intent patients matching your specific inclusion criteria.

Start Campaign
RECRUITING Not applicable ClinicalTrials.gov

Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners

Sponsor: Massachusetts General Hospital • ClinicalTrials.gov ID: NCT07018726

Registry updated: 2026-10-06
Ad

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Check Eligibility →

Description

The purpose of the present investigation is to test the efficacy of a virtual, brief (6 sessions) dyadic (patient and care-partner together) intervention to prevent chronic emotional distress in dyads where one person is diagnosed with Young Onset Dementia (YOD). Through this study, we seek to address the unmet need of preventing chronic emotional distress in YOD dyads through a feasible, acceptable and credible program, and ideally enhance resiliency and improve wellbeing and quality of life in both members of the dyad.

Interventions

  • Resilient Together-YOD (Behavioral)
    This is a 6 session dyadic (patient and spousal care-partner) intervention that teaches resiliency and interpersonal communication skills early after YOD diagnoses. It aims to decrease heightened symptoms of depression and anxiety among dyads to help them engage in important decisions around long term care-planning and optimize adjustment. The goal is to equip dyads with the necessary skills to cope and engage in meaningful, challenging conversations around care-planning, symptom deterioration, work/family planning to improve well-being in both members of the dyad.
  • Health Enhancement Program-YOD (Behavioral)
    This is a 6 session program that will deliver educational information to dyads and will mimic the dose and duration of Resilient Together. The program will not teach any individual and dyadic interpersonal skills, but will contain education on psychological distress and healthy behaviors. Sessions will also be delivered virtually.

Eligibility criteria

Inclusion Criteria: Patient Criteria: * 40 years of age or older * Diagnosis of young-onset dementia (FTD, PPA, AD, PCA, etc.) with symptom onset prior to age 65 or evidence of familial AD onset up to age 70 * Received YOD diagnosis in the past 10 months * English fluency and literacy * Cognitive ability to understand study and research protocol in order to consent to participation in intervention per referring neurologist and/or consent teach back questions * Must have a care-partner willing to participate Care-Partner Criteria: * 18 years of age or older * Care-partner to person diagnosed with young-onset dementia (FTD, PPA, AD, PCA, etc.) * English fluency and literacy Dyad Criteria: (Both Patient and Care-Partner): -At least one dyad member reports elevated emotional distress (HADS\>7) Exclusion Criteria: * An additional, terminal diagnosis such as cancer * Unwillingness to participate and use zoom for video conferencing * Current untreated or unstable severe mental health conditions like bipolar disorder, schizophrenia, or active substance use

Conditions

Young Onset Dementia

Locations

  • Massachusetts General Hospital (MGH) — Boston, Massachusetts, United States
Sponsored

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record