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ENDometriosis: Evaluation of Detection and Need for ALGOlogic Care Before Surgery

Sponsor: University Hospital, Limoges • ClinicalTrials.gov ID: NCT06997809

Registry updated: 2026-09-04

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Description

Endometriosis surgery is required when medical treatment fails to release women from pain. However, complete surgery does not work every time to improve patients' symptoms. Algological care is one of the options to treat the pain before surgery and their related complications (neuropathy, sensitization, and catastrophism) that could be associated to nociceptive pain. But not all patients could benefit from this pathway and no screening strategy does exist to detect these complications that could be treated prior to endometriosis surgery

Interventions

pathway care (Other)
Group for whom the test results will be used to determine the management strategy. If one of the tests performed before randomization is positive an algological consultation before surgery will be performed with an adapted treatment. Then surgical treatment as planned. If all tests are negative, surgical treatment is performed. The dedicated algology consultation must be done with an experienced practitioner different from the one who will perform the surgery. A rapid algological treatment circuit must be put in place to maintain the surgery date set. Group without using the results of test for associated pain components. Standard surgical treatment as planned through dedicated staff on endometriosis treatment.

Eligibility criteria

Inclusion criteria: * Maternal age from 18 up to 50 years old (50 non included). * Women affiliated to social coverage insurance * Women who understand French * Women who signed the written consent * Women with impaired quality of life (pain) linked to endometriosis * Women with formal radiological signs of endometriosis (MRI lesions more than 5 mm or endometrioma more than 20 mm on radiological examinations). * Surgical indication for resection of lesions by laparoscopy or robotic surgery for management of pain or impairment of quality of life * Patients requiring complete conservative or radical resections of all lesions * Indication of surgery validated within dedicated meeting for endometriosis. * Purpose of pain associated or not with infertility * Date of surgery fixed with sufficient time for algological treatment. Maximum delay of 4 months between randomization and surgery Exclusion criteria: * Women undergoing surgery for the purpose of infertility * Patient with previous surgery for removal of deep lesions of endometriosis or endometriotic cysts (history of exploratory laparoscopy accepted) * Patient with suspicious lesions on MRI or specialized ultrasound. * A patient who needs to be treated for another uterine pathology at the same time. * Pregnant women * Patient with a desire for pregnancy immediately and/or within one year after surgery * Women who refuse clinical examination (some algological tests couldn't be performed without clinical examination) * Patient who has already received algological treatment or who should receive it before surgery * Patient with previous other psychiatric disorders (depressive symptoms treated) * Women without rights

Conditions

Endometriosis, Pain

Locations

Bordeaux University Hospital — Bordeaux, France, France
IFEMENDO — Bordeaux, France, France
Versailles Hospital — Le Chesnay, France, France
Saint-Vincent-de-Paul Hospital — Lille, France, France
Limoges University hospital — Limoges, France, France
Poissy-St-Germain Intercommunal hospital center — Poissy, France, France
Poitiers University Hospital — Poitiers, France, France
Mutual Clinic La Sagesse — Rennes, France, France
South Hospital Rennes University Hospital — Rennes, France, France

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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