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RECRUITING Not applicable ClinicalTrials.gov

A Study of the MIND Diet for Persons With Multiple Sclerosis

Sponsor: Icahn School of Medicine at Mount Sinai • ClinicalTrials.gov ID: NCT06992115

Registry updated: 2026-10-02
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Description

This study will assess the impact of a MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet on brain health and MS symptoms. Participants will be randomly assigned to one of two arms: the diet intervention arm or the "continue current diet"/control arm. Participants randomized to the dietary intervention arm will change their diet to follow a MIND dietary pattern for one year; diet-related education and programming is provided to support this change. Participants randomized to the continue/control arm will be asked to continue their current dietary habits, without major change for one year; multiple sclerosis (MS) MS-related related education and programming (unrelated to diet) is provided. All participants will be asked to provide blood \& stool samples and to complete online questionnaires \& three in-person assessments.

Interventions

  • Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet (Behavioral)
    A dietary pattern which promotes the intake of olive oil, fish, leafy greens \& other vegetables, fruits, whole grains, and legumes, and discourages processed foods, red meat, and sugar.
  • Small Group (Behavioral)
    Education and social support on topics related to multiple sclerosis such as disease-modifying therapies and MRI in MS.

Eligibility criteria

Inclusion Criteria: * Ages 18-70 years, inclusive * MS diagnosis, on any treatment (including no treatment) * MIND diet score of ≤9 at baseline Exclusion Criteria: * Diagnosis of an additional neurodegenerative disease (e.g. Alzheimer's) or other serious neurological condition (e.g. stroke) * Current serious medical condition that could impact the ability to participate or influence study results (e.g. cancer, HIV) * Pregnancy/planning during study period

Conditions

Multiple Sclerosis

Locations

  • Mount Sinai Hospital — New York, New York, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record