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RECRUITING Phase 3 ClinicalTrials.gov

A Study of Changes to Prostate Procedures

Sponsor: Memorial Sloan Kettering Cancer Center • ClinicalTrials.gov ID: NCT06986083

Registry updated: 2026-09-15
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Description

The purpose of this study is to look whether using local anesthesia during a transperineal prostate biopsy, while put to sleep by IV sedation, helps reduce the number of people who feel significant pain in the recovery room. The researchers will also look at how local anesthesia affects the amount of pain medication used, how quickly people can go home after the biopsy, and how well they recover after leaving the hospital.

Interventions

  • Prostate Biopsy (Procedure)
    Transperineal prostate biopsy
  • Local anesthesia (Drug)
    Local anesthesia in addition to IV sedation

Eligibility criteria

Inclusion Criteria: Local anesthesia versus no local anesthesia during transperineal biopsy, while the patient is under IV sedation: * Patients scheduled for transperineal prostate biopsy at the JRSC or Monmouth. Standardization of a periprocedural pathway versus usual care for focal gland ablation: * Patients scheduled for a partial prostate gland ablation procedure at the JRSC. Exclusion Criteria: Local anesthesia versus no local anesthesia during transperineal biopsy, while patient is under IV sedation: * None Standardization of a periprocedural pathway versus usual care for focal gland ablation: * None

Conditions

Prostate Cancer

Locations

  • Memorial Sloan Kettering Cancer Center at Basking Ridge (Consent Only) — Basking Ridge, New Jersey, United States
  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities) — Middletown, New Jersey, United States
  • Memorial Sloan Kettering Bergen (Consent Only) — Montvale, New Jersey, United States
  • Memorial Sloan Kettering Suffolk-Commack (Consent only) — Commack, New York, United States
  • Memorial Sloan Kettering Westchester (Consent Only) — Harrison, New York, United States
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities) — New York, New York, United States
  • Memorial Sloan Kettering Nassau (Consent Only) — Uniondale, New York, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record