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RECRUITING Phase 3 ClinicalTrials.gov

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

Sponsor: NRG Oncology • ClinicalTrials.gov ID: NCT06958328

Registry updated: 2026-08-25
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Description

This phase III trial compares the effect of dose-escalated radiation therapy to usual care in patients with locally advanced unresectable pancreatic ductal adenocarcinoma who have received an initial 4-8 months of chemotherapy. Usual care options include additional chemotherapy, observation, or standard lower-dose radiation therapy. These treatments may delay tumor growth but have not been shown to improve survival. Radiation therapy uses high energy X-rays to kill cancer cells and shrink tumors. Dose-escalated radiation therapy involves the precise delivery of higher doses to the tumor, often over a shorter period of time. This trial assesses whether using dose-escalated radiation therapy can prolong survival.

Interventions

  • Biopsy Procedure (Procedure)
    Undergo tumor tissue biopsy
  • Biospecimen Collection (Procedure)
    Undergo blood sample collection
  • Capecitabine (Drug)
    Given capecitabine
  • Computed Tomography (Procedure)
    Undergo CT or PET/CT
  • Dose-escalated Radiation Therapy (Radiation)
    Undergo dose-escalated radiation using intensity-modulated radiation therapy treatment planning
  • Fluorouracil (Drug)
    Given fluorouracil
  • Gemcitabine (Drug)
    Given gemcitabine
  • Irinotecan Hydrochloride (Drug)
    Given irinotecan hydrochloride
  • Irinotecan Sucrosofate (Drug)
    Given liposomal irinotecan
  • Leucovorin Calcium (Drug)
    Given leucovorin calcium
  • Magnetic Resonance Imaging (Procedure)
    Undergo MRI
  • Nab-paclitaxel (Drug)
    Given nab-paclitaxel
  • Observation Activity (Other)
    Undergo observation
  • Oxaliplatin (Drug)
    Given oxaliplatin
  • Positron Emission Tomography (Procedure)
    Undergo PET/CT
  • Questionnaire Administration (Other)
    Ancillary studies
  • Radiation Therapy (Radiation)
    Undergo standard radiation therapy
  • Tumor Treating Fields Therapy (Procedure)
    Undergo TTF

Eligibility criteria

Inclusion Criteria: * At time of enrollment, the patient must have received 4-8 months of active chemotherapy with FOLFIRINOX or NALIRIFOX or gemcitabine/nab-paclitaxel. Patients are permitted to receive more than 1 type of chemotherapy for reasons other than radiographic progression by Response Evaluation Criteria in Solid Tumors (RECIST) (i.e. chemotherapy regimen switch is allowed for toxicity, and/or switch is allowed for toxicity and/or CA19-9 level not declining). Patients are allowed to receive chemotherapy after restaging scans, as long as 1) restaging scans are performed after at least 4 months of chemotherapy and 2) the total chemotherapy duration does not exceed 8 months * "Active chemotherapy" refers to time on chemotherapy not counting treatment breaks (i.e. if a patient had 1 month of chemotherapy followed by 1 month break, this would count as 1 month chemotherapy). Study registration must occur within 45 days of last day of pre-study entry chemotherapy * BASELINE PRE-ENTRY CHEMOTHERAPY REQUIREMENTS: * Pathologically (histologically or cytologically) proven diagnosis of pancreatic ductal adenocarcinoma * Locally advanced unresectable disease (as defined per the National Comprehensive Cancer Network \[NCCN\] guidelines and institutional tumor board review) * Patients must have baseline pre-chemotherapy scans for staging. Options include: CT chest/abdomen/pelvis, CT chest/MRI abdomen/pelvis, CT chest/CT pelvis/MRI abdomen, or PET/CT performed prior to enrollment * Age ≥ 18 years * Performance status Eastern Cooperative Oncology Group (ECOG) 0-2 * Required initial laboratory values: All laboratory values must be obtained any time prior to initiation of chemotherapy up to 30 days post initiation of chemotherapy * Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 3 x upper limit of normal (ULN) * BASELINE CA19-9 AND BILIRUBIN REQUIREMENTS: The purpose is to obtain a baseline CA19-9 in the setting of a normal (or close to normal) bilirubin, since serologic response by serial CA19-9 measurements is part of post-chemotherapy eligibility criteria * If baseline CA19-9 \> 37 U/mL the concurrent bilirubin must be ≤ 1.5 x ULN. (Note: if the bilirubin is not ≤ 1.5 x ULN both the CA19-9 and concurrent bilirubin can be repeated until bilirubin is ≤ 1.5 x ULN, as long as done within specified timeframe \[up to 30 days post chemotherapy initiation\]) * If baseline CA19-9 U/mL ≤ 37, there are no restrictions on the required concurrent bilirubin level, and this can be the accepted baseline value * Prior radiation treatment * Has the patient had prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields * Prior non-overlapping radiation (e.g., breast, head and neck, extremity) is permitted * If uncertain about prior overlap, please contact the study principal investigator, Dr. Nina Sanford * POST PRE-ENTRY CHEMOTHERAPY REQUIREMENTS: * If baseline CA19-9 is elevated (defined as \> 37 u/mL) the post-pre-entry chemotherapy CA19-9 must be less than 200 u/mL OR a 70% decline from pre-chemotherapy level (i.e. a patient with post induction chemotherapy CA199 value ≥ 200 u/mL would qualify, as long as they had at least 70% drop from baseline CA199 value; similarly, a patient with less than a 70% decline would qualify as long as absolute value post induction chemotherapy is under 200 u/mL) (must be completed any time post month 4 of chemotherapy and prior to study entry) * If baseline CA19-9 is not elevated (defined as ≤ 37 u/mL) the post-pre-entry chemotherapy CA19-9 must remain ≤ 37 u/mL (must be completed any time post month 4 of chemotherapy and prior to study entry) * No active duodenal or gastric ulcers * No direct tumor invasion of the bowel or stomach * Restaging scans showing at least stable disease (no progression). Options for scans include: CT chest/abdomen/pelvis, CT chest/MRI abdomen/pelvis, or CT chest/CT pelvis/MRI abdomen, or PET/CT performed prior to enrollment, with restaging CT showing at least stable disease * Not pregnant and not nursing * No cardiac condition that was the primary reason for hospitalization in the last 6 months * New York Heart Association Functional Classification II or better (NYHA Functional Classification III/IV are not eligible) (Note: Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification.) * HIV-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial

Conditions

Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma Stage II Pancreatic Cancer AJCC v8 Stage III Pancreatic Cancer AJCC v8 Stage IV Pancreatic Cancer AJCC v8

Locations

  • Banner MD Anderson Cancer Center — Gilbert, Arizona, United States
  • Arizona Center for Cancer Care - Gilbert — Gilbert, Arizona, United States
  • Arizona Center for Cancer Care-Peoria — Peoria, Arizona, United States
  • Banner-University Medical Center Phoenix — Phoenix, Arizona, United States
  • Arizona Center for Cancer Care - Phoenix — Phoenix, Arizona, United States
  • Arizona Center for Cancer Care - Scottsdale — Scottsdale, Arizona, United States
  • Arizona Center for Cancer Care-Surprise — Surprise, Arizona, United States
  • Arizona Center for Cancer Care — Tempe, Arizona, United States
  • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro — Jonesboro, Arkansas, United States
  • Mission Hope Medical Oncology - Arroyo Grande — Arroyo Grande, California, United States
  • AIS Cancer Center at San Joaquin Community Hospital — Bakersfield, California, United States
  • Alta Bates Summit Medical Center-Herrick Campus — Berkeley, California, United States
  • Mills-Peninsula Medical Center — Burlingame, California, United States
  • Sutter Cancer Centers Radiation Oncology Services-Cameron Park — Cameron Park, California, United States
  • Palo Alto Medical Foundation-Fremont — Fremont, California, United States
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care — Irvine, California, United States
  • UC San Diego Moores Cancer Center — La Jolla, California, United States
  • Memorial Medical Center — Modesto, California, United States
  • Palo Alto Medical Foundation-Camino Division — Mountain View, California, United States
  • UC Irvine Health/Chao Family Comprehensive Cancer Center — Orange, California, United States
  • Palo Alto Medical Foundation Health Care — Palo Alto, California, United States
  • Stanford Cancer Institute Palo Alto — Palo Alto, California, United States
  • Sutter Cancer Centers Radiation Oncology Services-Roseville — Roseville, California, United States
  • Sutter Roseville Medical Center — Roseville, California, United States
  • Sutter Medical Center Sacramento — Sacramento, California, United States
  • California Pacific Medical Center-Pacific Campus — San Francisco, California, United States
  • Mills Health Center — San Mateo, California, United States
  • Ridley-Tree Cancer Center — Santa Barbara, California, United States
  • Mission Hope Medical Oncology - Santa Maria — Santa Maria, California, United States
  • Sutter Pacific Medical Foundation — Santa Rosa, California, United States
  • Palo Alto Medical Foundation-Sunnyvale — Sunnyvale, California, United States
  • Sutter Solano Medical Center/Cancer Center — Vallejo, California, United States
  • BASS Medical Group - Lennon — Walnut Creek, California, United States
  • Rocky Mountain Cancer Centers-Boulder — Boulder, Colorado, United States
  • Rocky Mountain Cancer Centers-Penrose — Colorado Springs, Colorado, United States
  • UCHealth Memorial Hospital Central — Colorado Springs, Colorado, United States
  • Memorial Hospital North — Colorado Springs, Colorado, United States
  • AdventHealth Porter — Denver, Colorado, United States
  • AdventHealth Littleton — Littleton, Colorado, United States
  • AdventHealth Parker — Parker, Colorado, United States
  • Danbury Hospital — Danbury, Connecticut, United States
  • Smilow Cancer Hospital-Derby Care Center — Derby, Connecticut, United States
  • Smilow Cancer Hospital Care Center-Fairfield — Fairfield, Connecticut, United States
  • Smilow Cancer Hospital Care Center at Glastonbury — Glastonbury, Connecticut, United States
  • Smilow Cancer Hospital Care Center at Greenwich — Greenwich, Connecticut, United States
  • Smilow Cancer Hospital Care Center - Guilford — Guilford, Connecticut, United States
  • Smilow Cancer Hospital-Hamden Care Center — Hamden, Connecticut, United States
  • Smilow Cancer Hospital Care Center at Saint Francis — Hartford, Connecticut, United States
  • Smilow Cancer Center/Yale-New Haven Hospital — New Haven, Connecticut, United States
  • Yale University — New Haven, Connecticut, United States
  • Yale-New Haven Hospital North Haven Medical Center — North Haven, Connecticut, United States
  • Norwalk Hospital — Norwalk, Connecticut, United States
  • Smilow Cancer Hospital-Torrington Care Center — Torrington, Connecticut, United States
  • Smilow Cancer Hospital Care Center-Trumbull — Trumbull, Connecticut, United States
  • Smilow Cancer Hospital-Waterbury Care Center — Waterbury, Connecticut, United States
  • Smilow Cancer Hospital Care Center - Waterford — Waterford, Connecticut, United States
  • Helen F Graham Cancer Center — Newark, Delaware, United States
  • Medical Oncology Hematology Consultants PA — Newark, Delaware, United States
  • Christiana Care Health System-Christiana Hospital — Newark, Delaware, United States
  • Christiana Care Health System-Wilmington Hospital — Wilmington, Delaware, United States
  • MedStar Washington Hospital Center — Washington D.C., District of Columbia, United States
  • Morton Plant Hospital — Clearwater, Florida, United States
  • UF Health Cancer Institute - Gainesville — Gainesville, Florida, United States
  • Miami Cancer Institute — Miami, Florida, United States
  • AdventHealth Orlando — Orlando, Florida, United States
  • Saint Joseph's Hospital/Children's Hospital-Tampa — Tampa, Florida, United States
  • Grady Health System — Atlanta, Georgia, United States
  • Emory University Hospital Midtown — Atlanta, Georgia, United States
  • Piedmont Hospital — Atlanta, Georgia, United States
  • Emory University Hospital/Winship Cancer Institute — Atlanta, Georgia, United States
  • Emory Saint Joseph's Hospital — Atlanta, Georgia, United States
  • Memorial Health University Medical Center — Savannah, Georgia, United States
  • Hawaii Cancer Care Inc - Waterfront Plaza — Honolulu, Hawaii, United States
  • Queen's Cancer Cenrer - POB I — Honolulu, Hawaii, United States
  • Queen's Medical Center — Honolulu, Hawaii, United States
  • Straub Clinic and Hospital — Honolulu, Hawaii, United States
  • University of Hawaii Cancer Center — Honolulu, Hawaii, United States
  • Kuakini Medical Center — Honolulu, Hawaii, United States
  • Queen's Cancer Center - Kuakini — Honolulu, Hawaii, United States
  • The Cancer Center of Hawaii-Liliha — Honolulu, Hawaii, United States
  • Kapiolani Medical Center for Women and Children — Honolulu, Hawaii, United States
  • Wilcox Memorial Hospital and Kauai Medical Clinic — Lihue, Hawaii, United States
  • Hawaii Cancer Care - Westridge — ‘Aiea, Hawaii, United States
  • Pali Momi Medical Center — ‘Aiea, Hawaii, United States
  • Queen's Cancer Center - Pearlridge — ‘Aiea, Hawaii, United States
  • The Cancer Center of Hawaii-Pali Momi — ‘Aiea, Hawaii, United States
  • The Queen's Medical Center - West Oahu — ‘Ewa Beach, Hawaii, United States
  • Rush-Copley Medical Center — Aurora, Illinois, United States
  • Advocate Outpatient Center - Aurora — Aurora, Illinois, United States
  • Illinois CancerCare-Bloomington — Bloomington, Illinois, United States
  • Illinois CancerCare-Canton — Canton, Illinois, United States
  • Illinois CancerCare-Carthage — Carthage, Illinois, United States
  • Centralia Oncology Clinic — Centralia, Illinois, United States
  • Northwestern University — Chicago, Illinois, United States
  • University of Illinois — Chicago, Illinois, United States
  • Advocate Illinois Masonic Medical Center — Chicago, Illinois, United States
  • AMG Crystal Lake - Oncology — Crystal Lake, Illinois, United States
  • Carle at The Riverfront — Danville, Illinois, United States
  • Cancer Care Specialists of Illinois - Decatur — Decatur, Illinois, United States
  • Decatur Memorial Hospital — Decatur, Illinois, United States
  • Northwestern Medicine Cancer Center Kishwaukee — DeKalb, Illinois, United States
  • Advocate Good Samaritan Hospital — Downers Grove, Illinois, United States
  • Carle Physician Group-Effingham — Effingham, Illinois, United States
  • Crossroads Cancer Center — Effingham, Illinois, United States
  • Advocate Sherman Hospital — Elgin, Illinois, United States
  • Illinois CancerCare-Eureka — Eureka, Illinois, United States
  • Illinois CancerCare-Galesburg — Galesburg, Illinois, United States
  • Northwestern Medicine Cancer Center Delnor — Geneva, Illinois, United States
  • Northwestern Medicine Glenview Outpatient Center — Glenview, Illinois, United States
  • Northwestern Medicine Grayslake Outpatient Center — Grayslake, Illinois, United States
  • Advocate South Suburban Hospital — Hazel Crest, Illinois, United States
  • Illinois CancerCare-Kewanee Clinic — Kewanee, Illinois, United States
  • Northwestern Medicine Lake Forest Hospital — Lake Forest, Illinois, United States
  • AMG Libertyville - Oncology — Libertyville, Illinois, United States
  • Condell Memorial Hospital — Libertyville, Illinois, United States
  • Illinois CancerCare-Macomb — Macomb, Illinois, United States
  • Carle Physician Group-Mattoon/Charleston — Mattoon, Illinois, United States
  • Cancer Care Center of O'Fallon — O'Fallon, Illinois, United States
  • HSHS Saint Elizabeth's Hospital — O'Fallon, Illinois, United States
  • Northwestern Medicine Oak Brook — Oak Brook, Illinois, United States
  • Advocate Christ Medical Center — Oak Lawn, Illinois, United States
  • Illinois CancerCare-Ottawa Clinic — Ottawa, Illinois, United States
  • Advocate High Tech Medical Park — Palos Heights, Illinois, United States
  • Advocate Lutheran General Hospital — Park Ridge, Illinois, United States
  • Illinois CancerCare-Pekin — Pekin, Illinois, United States
  • Illinois CancerCare-Peoria — Peoria, Illinois, United States
  • OSF Saint Francis Medical Center — Peoria, Illinois, United States
  • Illinois CancerCare-Peru — Peru, Illinois, United States
  • Illinois CancerCare-Princeton — Princeton, Illinois, United States
  • Southern Illinois University School of Medicine — Springfield, Illinois, United States
  • Springfield Clinic — Springfield, Illinois, United States
  • Springfield Memorial Hospital — Springfield, Illinois, United States
  • Carle Cancer Center — Urbana, Illinois, United States
  • Northwestern Medicine Cancer Center Warrenville — Warrenville, Illinois, United States
  • Illinois CancerCare - Washington — Washington, Illinois, United States
  • Northwest Cancer Center - Crown Point — Crown Point, Indiana, United States
  • Northwest Oncology LLC — Dyer, Indiana, United States
  • Goshen Center for Cancer Care — Goshen, Indiana, United States
  • Northwest Cancer Center - Hobart — Hobart, Indiana, United States
  • Saint Mary Medical Center — Hobart, Indiana, United States
  • The Community Hospital — Munster, Indiana, United States
  • Women's Diagnostic Center - Munster — Munster, Indiana, United States
  • Northwest Cancer Center - Valparaiso — Valparaiso, Indiana, United States
  • UI Health Care Mission Cancer and Blood - Ankeny Clinic — Ankeny, Iowa, United States
  • UI Health Care Mission Cancer and Blood - West Des Moines Clinic — Clive, Iowa, United States
  • Iowa Methodist Medical Center — Des Moines, Iowa, United States
  • UI Health Care Mission Cancer and Blood - Des Moines Clinic — Des Moines, Iowa, United States
  • UI Health Care Mission Cancer and Blood - Laurel Clinic — Des Moines, Iowa, United States
  • UI Health Care Mission Cancer and Blood - Waukee Clinic — Waukee, Iowa, United States
  • University of Kansas Cancer Center — Kansas City, Kansas, United States
  • Lawrence Memorial Hospital — Lawrence, Kansas, United States
  • The University of Kansas Cancer Center - Olathe — Olathe, Kansas, United States
  • University of Kansas Cancer Center-Overland Park — Overland Park, Kansas, United States
  • Salina Regional Health Center — Salina, Kansas, United States
  • University of Kansas Health System Saint Francis Campus — Topeka, Kansas, United States
  • University of Kansas Hospital-Westwood Cancer Center — Westwood, Kansas, United States
  • University of Kentucky/Markey Cancer Center — Lexington, Kentucky, United States
  • West Jefferson Medical Center — Marrero, Louisiana, United States
  • University Medical Center New Orleans — New Orleans, Louisiana, United States
  • MaineHealth Coastal Cancer Treatment Center — Bath, Maine, United States
  • MaineHealth Maine Medical Center - Portland — Portland, Maine, United States
  • MaineHealth Cancer Care Center of York County — Sanford, Maine, United States
  • MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine, United States
  • MaineHealth Cancer Care and IV Therapy - South Portland — South Portland, Maine, United States
  • Sinai Hospital of Baltimore — Baltimore, Maryland, United States
  • William E Kahlert Regional Cancer Center/Sinai Hospital — Westminster, Maryland, United States
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor — Ann Arbor, Michigan, United States
  • University of Michigan Rogel Cancer Center — Ann Arbor, Michigan, United States
  • Trinity Health IHA Medical Group Hematology Oncology - Brighton — Brighton, Michigan, United States
  • Trinity Health Medical Center - Brighton — Brighton, Michigan, United States
  • University of Michigan - Brighton Center for Specialty Care — Brighton, Michigan, United States
  • Henry Ford Cancer Institute-Downriver — Brownstown, Michigan, United States
  • Trinity Health IHA Medical Group Hematology Oncology - Canton — Canton, Michigan, United States
  • Trinity Health Medical Center - Canton — Canton, Michigan, United States
  • Chelsea Hospital — Chelsea, Michigan, United States
  • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital — Chelsea, Michigan, United States
  • Henry Ford Macomb Hospital-Clinton Township — Clinton Township, Michigan, United States
  • Henry Ford Medical Center-Fairlane — Dearborn, Michigan, United States
  • Henry Ford Hospital — Detroit, Michigan, United States
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital — Grand Rapids, Michigan, United States
  • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital — Grand Rapids, Michigan, United States
  • Trinity Health Grand Rapids Hospital — Grand Rapids, Michigan, United States
  • Allegiance Health — Jackson, Michigan, United States
  • Bronson Methodist Hospital — Kalamazoo, Michigan, United States
  • West Michigan Cancer Center — Kalamazoo, Michigan, United States
  • Beacon Kalamazoo — Kalamazoo, Michigan, United States
  • University of Michigan Health - Sparrow Lansing — Lansing, Michigan, United States
  • Trinity Health Saint Mary Mercy Livonia Hospital — Livonia, Michigan, United States
  • Henry Ford Medical Center-Columbus — Novi, Michigan, United States
  • Michigan Healthcare Professionals Pontiac — Pontiac, Michigan, United States
  • Trinity Health Saint Joseph Mercy Oakland Hospital — Pontiac, Michigan, United States
  • MyMichigan Medical Center Saginaw — Saginaw, Michigan, United States
  • MyMichigan Medical Center Tawas — Tawas City, Michigan, United States
  • Henry Ford West Bloomfield Hospital — West Bloomfield, Michigan, United States
  • Henry Ford Wyandotte Hospital — Wyandotte, Michigan, United States
  • University of Michigan Health - West — Wyoming, Michigan, United States
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus — Ypsilanti, Michigan, United States
  • Sanford Joe Lueken Cancer Center — Bemidji, Minnesota, United States
  • Baptist Memorial Hospital and Cancer Center-Golden Triangle — Columbus, Mississippi, United States
  • Baptist Cancer Center-Grenada — Grenada, Mississippi, United States
  • Baptist Memorial Hospital and Cancer Center-Union County — New Albany, Mississippi, United States
  • Baptist Memorial Hospital and Cancer Center-Oxford — Oxford, Mississippi, United States
  • Baptist Memorial Hospital and Cancer Center-Desoto — Southhaven, Mississippi, United States
  • University of Kansas Cancer Center - North — Kansas City, Missouri, United States
  • University of Kansas Cancer Center - Lee's Summit — Lee's Summit, Missouri, United States
  • Nebraska Medicine-Village Pointe — Omaha, Nebraska, United States
  • University of Nebraska Medical Center — Omaha, Nebraska, United States
  • Renown Regional Medical Center — Reno, Nevada, United States
  • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center — Lebanon, New Hampshire, United States
  • Memorial Sloan Kettering Basking Ridge — Basking Ridge, New Jersey, United States
  • Cooper Hospital University Medical Center — Camden, New Jersey, United States
  • Jefferson Cherry Hill Hospital — Cherry Hill, New Jersey, United States
  • Memorial Sloan Kettering Monmouth — Middletown, New Jersey, United States
  • Memorial Sloan Kettering Bergen — Montvale, New Jersey, United States
  • New York-Presbyterian/Brooklyn Methodist Hospital — Brooklyn, New York, United States
  • Roswell Park Cancer Institute — Buffalo, New York, United States
  • Memorial Sloan Kettering Commack — Commack, New York, United States
  • Memorial Sloan Kettering Westchester — Harrison, New York, United States
  • NYU Langone Hospital - Long Island — Mineola, New York, United States
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone — New York, New York, United States
  • Mount Sinai West — New York, New York, United States
  • Mount Sinai Hospital — New York, New York, United States
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center — New York, New York, United States
  • Memorial Sloan Kettering Cancer Center — New York, New York, United States
  • Vassar Brothers Medical Center — Poughkeepsie, New York, United States
  • Montefiore Medical Center-Einstein Campus — The Bronx, New York, United States
  • Montefiore Medical Center - Moses Campus — The Bronx, New York, United States
  • Memorial Sloan Kettering Nassau — Uniondale, New York, United States
  • UNC Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina, United States
  • Sanford Bismarck Medical Center — Bismarck, North Dakota, United States
  • Sanford Broadway Medical Center — Fargo, North Dakota, United States
  • Sanford Roger Maris Cancer Center — Fargo, North Dakota, United States
  • Aultman Health Foundation — Canton, Ohio, United States
  • Miami Valley Hospital South — Centerville, Ohio, United States
  • University of Cincinnati Cancer Center-UC Medical Center — Cincinnati, Ohio, United States
  • Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States
  • Miami Valley Hospital — Dayton, Ohio, United States
  • Premier Blood and Cancer Center — Dayton, Ohio, United States
  • Miami Valley Hospital North — Dayton, Ohio, United States
  • Dublin Methodist Hospital — Dublin, Ohio, United States
  • Atrium Medical Center-Middletown Regional Hospital — Franklin, Ohio, United States
  • Miami Valley Cancer Care and Infusion — Greenville, Ohio, United States
  • ProMedica Flower Hospital — Sylvania, Ohio, United States
  • ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital — Toledo, Ohio, United States
  • Upper Valley Medical Center — Troy, Ohio, United States
  • University of Cincinnati Cancer Center-West Chester — West Chester, Ohio, United States
  • Oregon Health and Science University — Portland, Oregon, United States
  • Christiana Care Health System-Concord Health Center — Chadds Ford, Pennsylvania, United States
  • Geisinger Medical Center — Danville, Pennsylvania, United States
  • Geisinger Cancer Center Dickson City — Dickson City, Pennsylvania, United States
  • Jefferson Hospital — Jefferson Hills, Pennsylvania, United States
  • Geisinger Medical Oncology-Lewisburg — Lewisburg, Pennsylvania, United States
  • Forbes Hospital — Monroeville, Pennsylvania, United States
  • Paoli Memorial Hospital — Paoli, Pennsylvania, United States
  • Thomas Jefferson University Hospital — Philadelphia, Pennsylvania, United States
  • Jefferson Torresdale Hospital — Philadelphia, Pennsylvania, United States
  • Allegheny General Hospital — Pittsburgh, Pennsylvania, United States
  • West Penn Hospital — Pittsburgh, Pennsylvania, United States
  • Reading Hospital — West Reading, Pennsylvania, United States
  • Geisinger Wyoming Valley/Henry Cancer Center — Wilkes-Barre, Pennsylvania, United States
  • Rhode Island Hospital — Providence, Rhode Island, United States
  • Medical University of South Carolina — Charleston, South Carolina, United States
  • Saint Francis Hospital — Greenville, South Carolina, United States
  • Saint Francis Cancer Center — Greenville, South Carolina, United States
  • Sanford Cancer Center Oncology Clinic — Sioux Falls, South Dakota, United States
  • Sanford USD Medical Center - Sioux Falls — Sioux Falls, South Dakota, United States
  • Baptist Memorial Hospital and Cancer Center-Collierville — Collierville, Tennessee, United States
  • Regional Cancer Center at Johnson City Medical Center — Johnson City, Tennessee, United States
  • Baptist Memorial Hospital and Cancer Center-Memphis — Memphis, Tennessee, United States
  • Houston Methodist San Jacinto Hospital — Baytown, Texas, United States
  • UT MD Anderson - The Woodlands — Conroe, Texas, United States
  • Houston Methodist Cypress Hospital — Cypress, Texas, United States
  • Parkland Memorial Hospital — Dallas, Texas, United States
  • UT Southwestern Simmons Cancer Center - RedBird — Dallas, Texas, United States
  • UT Southwestern/Simmons Cancer Center-Dallas — Dallas, Texas, United States
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center — Houston, Texas, United States
  • Ben Taub General Hospital — Houston, Texas, United States
  • Houston Methodist Hospital — Houston, Texas, United States
  • UT MD Anderson Cancer Center — Houston, Texas, United States
  • Methodist Willowbrook Hospital — Houston, Texas, United States
  • UT MD Anderson - West Houston — Houston, Texas, United States
  • Houston Methodist West Hospital — Houston, Texas, United States
  • UT MD Anderson - League City — League City, Texas, United States
  • Houston Methodist Saint John Hospital — Nassau Bay, Texas, United States
  • University of Texas Health Science Center at San Antonio — San Antonio, Texas, United States
  • UT MD Anderson - Sugar Land — Sugar Land, Texas, United States
  • Houston Methodist Sugar Land Hospital — Sugar Land, Texas, United States
  • Houston Methodist The Woodlands Hospital — The Woodlands, Texas, United States
  • Dartmouth Cancer Center - North — Saint Johnsbury, Vermont, United States
  • Inova Alexandria Hospital — Alexandria, Virginia, United States
  • Inova Schar Cancer Institute — Fairfax, Virginia, United States
  • Inova Fair Oaks Hospital — Fairfax, Virginia, United States
  • Inova Fairfax Hospital — Falls Church, Virginia, United States
  • Inova Loudoun Hospital — Leesburg, Virginia, United States
  • Bon Secours Memorial Regional Medical Center — Mechanicsville, Virginia, United States
  • Bon Secours Saint Francis Medical Center — Midlothian, Virginia, United States
  • Bon Secours Saint Mary's Hospital — Richmond, Virginia, United States
  • Bon Secours Cancer Institute at Reynolds Crossing — Richmond, Virginia, United States
  • Fred Hutchinson Cancer Center — Seattle, Washington, United States
  • University of Washington Medical Center - Montlake — Seattle, Washington, United States
  • Edwards Comprehensive Cancer Center — Huntington, West Virginia, United States
  • Aspirus Cancer Care-Antigo-Volm Cancer Center — Antigo, Wisconsin, United States
  • Aurora Cancer Care-Southern Lakes VLCC — Burlington, Wisconsin, United States
  • Aurora Saint Luke's South Shore — Cudahy, Wisconsin, United States
  • Marshfield Medical Center-EC Cancer Center — Eau Claire, Wisconsin, United States
  • Aurora Health Care Germantown Health Center — Germantown, Wisconsin, United States
  • Aurora Cancer Care-Grafton — Grafton, Wisconsin, United States
  • Aurora BayCare Medical Center — Green Bay, Wisconsin, United States
  • Aurora Cancer Care-Kenosha South — Kenosha, Wisconsin, United States
  • Aurora Bay Area Medical Group-Marinette — Marinette, Wisconsin, United States
  • Marshfield Medical Center-Marshfield — Marshfield, Wisconsin, United States
  • Froedtert Menomonee Falls Hospital — Menomonee Falls, Wisconsin, United States
  • Aurora Cancer Care-Milwaukee — Milwaukee, Wisconsin, United States
  • Aurora Saint Luke's Medical Center — Milwaukee, Wisconsin, United States
  • Medical College of Wisconsin — Milwaukee, Wisconsin, United States
  • Aurora Sinai Medical Center — Milwaukee, Wisconsin, United States
  • Drexel Town Square Health Center — Oak Creek, Wisconsin, United States
  • Vince Lombardi Cancer Clinic - Oshkosh — Oshkosh, Wisconsin, United States
  • Aurora Cancer Care-Racine — Racine, Wisconsin, United States
  • Aspirus Cancer Care-Rhinelander-James Beck Cancer Center — Rhinelander, Wisconsin, United States
  • Marshfield Medical Center-Rice Lake — Rice Lake, Wisconsin, United States
  • Vince Lombardi Cancer Clinic-Sheboygan — Sheboygan, Wisconsin, United States
  • Aspirus Cancer Care - Stevens Point — Stevens Point, Wisconsin, United States
  • Marshfield Medical Center-River Region at Stevens Point — Stevens Point, Wisconsin, United States
  • Aurora Medical Center in Summit — Summit, Wisconsin, United States
  • Vince Lombardi Cancer Clinic-Two Rivers — Two Rivers, Wisconsin, United States
  • Aspirus Cancer Care-Wausau — Wausau, Wisconsin, United States
  • Aurora Cancer Care-Milwaukee West — Wauwatosa, Wisconsin, United States
  • Aurora West Allis Medical Center — West Allis, Wisconsin, United States
  • Froedtert West Bend Hospital/Kraemer Cancer Center — West Bend, Wisconsin, United States
  • Marshfield Medical Center - Weston — Weston, Wisconsin, United States
  • Aspirus Cancer Care - Wisconsin Rapids — Wisconsin Rapids, Wisconsin, United States
  • Cross Cancer Institute — Edmonton, Alberta, Canada
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record