RECRUITING Not applicable ClinicalTrials.gov

Caval Aorta Index for Fluid Optimization in Traumatic Brain Injury

Sponsor: Mansoura University • ClinicalTrials.gov ID: NCT06940258

Registry updated: 2026-10-13

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Description

Traumatic brain injury is a leading cause of death and disability in trauma patients. As the primary injury cannot be reversed; management strategies must focus on preventing secondary injury by avoiding hypotension and hypoxia besides, maintaining appropriate cerebral perfusion pressure, which is a surrogate for cerebral blood flow.

Interventions

ultrasound measurement of caval aorta index (Procedure)
ultrasound measurement of caval aorta index
control group (Other)
fixed fluid prescription

Eligibility criteria

Inclusion Criteria: Traumatic brain injury diagnosed by computed tomography scan Glasgow coma score ≥ 4 Exclusion Criteria: Inability to get consent. Pregnant and lactating women Traumatic subarachnoid hemorrhage Spinal cord injury Increased intra-abdominal pressure Abdominal aortic aneurysm Inferior vena cava (IVC) thrombus Portal hypertension Acute corpulmonale Congestive heart failure chronic hemodialysis Surgical intervention other than neurological one within the first 7 days Mechanical ventilation need during first 7 days Cardiac arrest during the first 7 days

Conditions

Fluid Balance

Locations

Mansoura University Hospitals — Al Mansurah, Egypt

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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