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RECRUITING Not applicable ClinicalTrials.gov

Traumatic Hemothorax Drainage and Daily Lavage

Sponsor: University of Pennsylvania • ClinicalTrials.gov ID: NCT06937450

Registry updated: 2026-09-11
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Description

This HTX treatment study evaluates the effects of chest tube size and the benefits of daily irrigations on acute HTX. 20 acutely injured but stable trauma patients requiring a chest tube for HTX will be enrolled. Patients will be assigned a 28Fr or 14 Fr chest tube with serial lavage and drainage. The endpoints will be HTX volume (by CT scan), complications, additional interventions, hospital length of stay, chest tube duration, provider feedback, and patient-reported outcomes.

Interventions

  • CLR Irrigator (Device)
    All enrolled patients will have their hemothorax treated with a CLR device that allows for easy suction and irrigation through indwelling catheters,
  • Serial Lavage and Drainage (Procedure)
    The current protocol is to do a singular lavage and drainage, this study will investigate the benefits of daily lavage.
  • 28 Fr Open Chest Tube (Device)
    Patients will have a standard 28 Fr open chest tube or a percutaneous 14Fr chest tube placed.
  • Percutaneous 14Fr Chest Tube (Device)
    Patients will have a standard 28 Fr open chest tube, or a percutaneous 14Fr chest tube placed.

Eligibility criteria

Inclusion Criteria: 1. Able to provide consent for the research study 2. More than 15 years of age 3. Presence of acute traumatic HTX or HTX-PTX diagnosed on chest CT scan within 24 hours of injury and clinical indication for drainage (hemothorax of moderate or large size greater then 300 mL) 4. Hemodynamic stability (heart rate 120 beats per minute; systolic blood pressure 90 mmHg) 5. Bilateral or unilateral hemothorax of greater than 300 mL HTX by Mergo Formula from chest CT 6. Able to complete the entire study including randomization, tube placement, lavages and final CT Scan. Exclusion Criteria: 1. Less than 15 years of Age 2. Prisoner 3. Pregnant due to the risk of CT scans 4. HTX or HTX-PTX not requiring drainage or drainage performed prior to randomization/enrollment 5. Patients undergoing operative intervention (i.e. thoracotomy) as initial management of hemothorax (6) Persistent hemodynamic instability after initial resuscitation and CT imaging

Conditions

Hemothorax; Traumatic

Locations

  • Penn Presbyterian Medical Center — Philadelphia, Pennsylvania, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record